KEGG   NETWORK: N01483
Entry
N01483                      Network                                
Name
Cohesin acetylation
Definition
HDAC8 -| ESCO1,ESCO2 -- SMC3 -> CDCA5
  Expanded
55869 -| 114799,157570 -- 9126 -> 113130
Class
nt06512 Chromosome cohesion and segregation
Type
Reference
Gene
55869  HDAC8; histone deacetylase 8
114799  ESCO1; establishment of sister chromatid cohesion N-acetyltransferase 1
157570  ESCO2; establishment of sister chromatid cohesion N-acetyltransferase 2
9126  SMC3; structural maintenance of chromosomes 3
113130  CDCA5; cell division cycle associated 5
Reference
  Authors
Boavida A, Santos D, Mahtab M, Pisani FM
  Title
Functional Coupling between DNA Replication and Sister Chromatid Cohesion Establishment.
  Journal
Int J Mol Sci 22:2810 (2021)
DOI:10.3390/ijms22062810
Reference
  Authors
Krantz ID
  Title
Cohesin embraces new phenotypes.
  Journal
Nat Genet 46:1157-8 (2014)
DOI:10.1038/ng.3123
Reference
  Authors
Deardorff MA, Bando M, Nakato R, Watrin E, Itoh T, Minamino M, Saitoh K, Komata M, Katou Y, Clark D, Cole KE, De Baere E, Decroos C, Di Donato N, Ernst S, Francey LJ, Gyftodimou Y, Hirashima K, Hullings M, Ishikawa Y, Jaulin C, Kaur M, Kiyono T, Lombardi PM, Magnaghi-Jaulin L, Mortier GR, Nozaki N, Petersen MB, Seimiya H, Siu VM, Suzuki Y, Takagaki K, Wilde JJ, Willems PJ, Prigent C, Gillessen-Kaesbach G, Christianson DW, Kaiser FJ, Jackson LG, Hirota T, Krantz ID, Shirahige K
  Title
HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle.
  Journal
Nature 489:313-7 (2012)
DOI:10.1038/nature11316
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