KEGG   NETWORK: N01528
Entry
N01528                      Network                                
Name
KSHV Kaposin to alternative pathway of complement cascade, C3b breakdown
Definition
C3b -- (CFI+KCP) -> iC3b -- (CFI+KCP) -> C3dg
  Expanded
C22533 -- (3426+K21649) -> C22535 -- (3426+K21649) -> C22536
Class
nt06513 Complement cascade
Type
Pathogen
Pathway
hsa05167  Kaposi sarcoma-associated herpesvirus infection
Disease
H00041  Kaposi sarcoma
Gene
3426  CFI; complement factor I
Perturbant
K21649 (KCP)  ORF4; KSHV complement control protein
Metabolite
C22533  Complement component 3b
C22535  Complement iC3b
C22536  Complement component 3dg
Reference
PMID:16905191
  Authors
Mark L, Spiller OB, Villoutreix BO, Blom AM
  Title
Kaposi's sarcoma-associated herpes virus complement control protein: KCP--complement inhibition and more.
  Journal
Mol Immunol 44:11-22 (2007)
DOI:10.1016/j.molimm.2006.06.018
Reference
PMID:12645526
  Authors
Spiller OB, Blackbourn DJ, Mark L, Proctor DG, Blom AM
  Title
Functional activity of the complement regulator encoded by Kaposi's sarcoma-associated herpesvirus.
  Journal
J Biol Chem 278:9283-9 (2003)
DOI:10.1074/jbc.m211579200
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