| Entry |
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| Name |
TSC1/2-mTORC1 signaling pathway
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| Definition |
(TSC1/2+TBC1D7) -| RHEB -> mTORC1 |
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| Expanded |
(7248+7249+51256) -| 6009 -> (2475+57521+84335+64798+64223+9894+9675) |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 7248 | TSC1; TSC complex subunit 1 |
| 7249 | TSC2; TSC complex subunit 2 |
| 51256 | TBC1D7; TBC1 domain family member 7 |
| 6009 | RHEB; Ras homolog, mTORC1 binding |
| 2475 | MTOR; mechanistic target of rapamycin kinase |
| 57521 | RPTOR; regulatory associated protein of MTOR complex 1 |
| 84335 | AKT1S1; AKT1 substrate 1 |
| 64798 | DEPTOR; DEP domain containing MTOR interacting protein |
| 64223 | MLST8; MTOR associated protein, LST8 homolog |
| 9894 | TELO2; telomere maintenance 2 |
| 9675 | TTI1; TELO2 interacting protein 1 |
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| Reference |
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| Authors |
Laplante M, Sabatini DM |
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| Title |
mTOR signaling at a glance. |
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| Journal |
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| Reference |
|
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| Authors |
Kennedy BK, Lamming DW |
|---|
| Title |
The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging. |
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| Journal |
|
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| Reference |
|
|---|
| Authors |
Caron A, Richard D, Laplante M |
|---|
| Title |
The Roles of mTOR Complexes in Lipid Metabolism. |
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| Journal |
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| LinkDB |
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