Homo sapiens (human): 64798
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Entry
64798 CDS
T01001
Symbol
DEPTOR, DEP.6, DEPDC6, hDEPTOR
Name
(RefSeq) DEP domain-containing mTOR-interacting protein isoform 1
KO
K20402
DEP domain-containing mTOR-interacting protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04140
Autophagy - animal
hsa04142
Lysosome biogenesis
hsa04150
mTOR signaling pathway
hsa04156
Integrated stress response (ISR) signaling pathway
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06461
Huntington disease
nt06462
Spinocerebellar ataxia
nt06466
Pathways of neurodegeneration
nt06522
mTOR signaling
nt06532
Autophagy
nt06551
Lysosome
Element
N00155
Autophagy-vesicle nucleation/elongation/maturation, mTORC1-PI3KC3-C1
N01575
TSC1/2-mTORC1 signaling pathway
N01578
GATOR1-mTORC1 signaling pathway
N01584
FLCN-mTORC1 signaling pathway
N02035
PI(3,5)P2 regulation by the PIKfyve complex
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04150 mTOR signaling pathway
64798 (DEPTOR)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome biogenesis
64798 (DEPTOR)
04140 Autophagy - animal
64798 (DEPTOR)
09143 Cell growth and death
04156 Integrated stress response (ISR) signaling pathway
64798 (DEPTOR)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
64798 (DEPTOR)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Other autophagy associated proteins
mTORC1 complex
64798 (DEPTOR)
mTORC2 complex
64798 (DEPTOR)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DEP
PDZ_6
GPAT_C
PDZ
Motif
Other DBs
NCBI-GeneID:
64798
NCBI-ProteinID:
NP_073620
OMIM:
612974
HGNC:
22953
Ensembl:
ENSP00000286234.5
UniProt:
Q8TB45
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:119873722..120050918
Genome browser
AA seq
409 aa
AA seq
DB search
MEEGGSTGSAGSDSSTSGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTY
PNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKD
DGTFPLDNEVKAFMRGQRLYEKLMSPENTLLQPREEEGVKYERTFMASEFLDWLVQEGEA
TTRKEAEQLCHRLMEHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLNEKSPSSQE
THDSPFCLRKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSP
PVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGP
AAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLILTGPRTIVMEVMEELEC
NT seq
1230 nt
NT seq
+upstream
nt +downstream
nt
atggaggagggcggcagcactggcagtgctggcagtgacagcagcaccagcgggagtggc
ggggcgcagcaaagggagctggagcgcatggctgaggtcttggtcaccggggaacagcta
cggctcaggctgcacgaagaaaaggttattaaagatagacgtcatcatctcaagacctac
ccaaactgttttgtcgcaaaagaactgattgactggctgattgaacacaaagaggcttct
gacagagagacggcaattaaactcatgcagaaattagcagaccggggcattattcaccat
gtgtgtgatgagcataaggaattcaaggatgtcaaactcttctaccgctttagaaaggat
gacggcaccttcccattggataatgaagtgaaggcctttatgagaggacagaggctatat
gaaaagctgatgagccctgaaaacacactcctgcagcccagggaggaggaaggggtcaag
tatgagcgcaccttcatggcatctgaattcctggactggctggttcaggaaggtgaggcc
accacgaggaaagaggcagagcagctttgccaccggcttatggagcatggcatcatccag
catgtgtccaacaagcacccatttgtggacagcaatcttctctaccagttcagaatgaac
ttccggcggaggcgaagactgatggagctgctcaatgaaaagtccccctcctcccaggaa
actcatgacagtcccttctgcctgaggaagcagagccatgacaatcggaaatctaccagc
tttatgtcagtgagccccagcaaggagatcaagatcgtgtctgcagtgaggagaagcagc
atgagcagctgtggcagcagcggctacttcagcagcagccccaccctcagcagcagcccc
cctgtgctctgcaaccccaagtccgtgctgaagagacctgtcacctctgaggaactcctt
actcccggggctccgtatgcaaggaagacattcacgattgttggtgacgcggttggctgg
ggttttgtggtgcgaggaagtaagccatgccacatccaggctgtagaccccagtggccct
gcagccgcagcaggaatgaaggtctgtcagtttgtcgtctctgtcaacgggctcaatgtc
ctgcatgtagactaccggaccgtgagcaatctgattctgacgggcccacggacgattgtc
atggaagtcatggaggagttagagtgctga
DBGET
integrated database retrieval system
