KEGG   NETWORK: N01585
Entry
N01585                      Network                                
Name
Deubiquitination of H2AK119
Definition
PR-DUB -| cPRC1
  Expanded
8314+(171023,55252,80816)+(8473+3054+221937,3607+7528+55777,114785) -| (7703,648)+(6015,6045)+(84733,8535,23466,23492,57332)+(22955,6322,10389)+(1911+1912+80012)
Class
nt06523 Epigenetic regulation by Polycomb complexes
Type
Reference
Gene
8314  BAP1; BRCA1 associated protein 1
171023  ASXL1; ASXL transcriptional regulator 1
55252  ASXL2; ASXL transcriptional regulator 2
80816  ASXL3; ASXL transcriptional regulator 3
8473  OGT; O-linked N-acetylglucosamine (GlcNAc) transferase
3054  HCFC1; host cell factor C1
221937  FOXK1; forkhead box K1
3607  FOXK2; forkhead box K2
7528  YY1; YY1 transcription factor
55777  MBD5; methyl-CpG binding domain protein 5
114785  MBD6; methyl-CpG binding domain protein 6
7703  PCGF2; polycomb group ring finger 2
648  BMI1; BMI1 proto-oncogene, polycomb ring finger
6015  RING1; ring finger protein 1
6045  RNF2; ring finger protein 2
84733  CBX2; chromobox 2
8535  CBX4; chromobox 4
23466  CBX6; chromobox 6
23492  CBX7; chromobox 7
57332  CBX8; chromobox 8
22955  SCMH1; Scm polycomb group protein homolog 1
6322  SCML1; Scm polycomb group protein like 1
10389  SCML2; Scm polycomb group protein like 2
1911  PHC1; polyhomeotic homolog 1
1912  PHC2; polyhomeotic homolog 2
80012  PHC3; polyhomeotic homolog 3
Reference
  Authors
Barbour H, Daou S, Hendzel M, Affar EB
  Title
Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes.
  Journal
Nat Commun 11:5947 (2020)
DOI:10.1038/s41467-020-19722-9
Reference
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
  Authors
Szczepanski AP, Wang L
  Title
Emerging multifaceted roles of BAP1 complexes in biological processes.
  Journal
Cell Death Discov 7:20 (2021)
DOI:10.1038/s41420-021-00406-2
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