Homo sapiens (human): 171023
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Entry
171023 CDS
T01001
Symbol
ASXL1, BOPS, MDS
Name
(RefSeq) ASXL transcriptional regulator 1
KO
K11471
additional sex combs-like protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa03083
Polycomb repressive complex
Network
nt06523
Epigenetic regulation by Polycomb complexes
Element
N01585
Deubiquitination of H2AK119
Disease
H01481
Myelodysplastic syndrome
H02047
Bohring-Opitz syndrome
H02410
Myelodysplastic/myeloproliferative neoplasms
H02411
Chronic myelomonocytic leukemia
H02412
Atypical chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
171023 (ASXL1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
171023 (ASXL1)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Histone modification proteins
Polycomb repressive complex (PRC) and associated proteins
PR-DUB complex
171023 (ASXL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ASXH
PHD_3
HARE-HTH
Motif
Other DBs
NCBI-GeneID:
171023
NCBI-ProteinID:
NP_056153
OMIM:
612990
HGNC:
18318
Ensembl:
ENSG00000171456
UniProt:
Q8IXJ9
Structure
PDB
PDBj
LinkDB
All DBs
Position
20:32358331..32439319
Genome browser
AA seq
1541 aa
AA seq
DB search
MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMRSGTSPLACLNAML
HSNSRGGEGLFYKLPGRISLFTLKKDALQWSRHPATVEGEEPEDTADVESCGSNEASTVS
GENDVSLDETSSNASCSTESQSRPLSNPRDSYRASSQANKQKKKTGVMLPRVVLTPLKVN
GAHVESASGFSGCHADGESGSPSSSSSGSLALGSAAIRGQAEVTQDPAPLLRGFRKPATG
QMKRNRGEEIDFETPGSILVNTNLRALINSRTFHALPSHFQQQLLFLLPEVDRQVGTDGL
LRLSSSALNNEFFTHAAQSWRERLADGEFTHEMQVRIRQEMEKEKKVEQWKEKFFEDYYG
QKLGLTKEESLQQNVGQEEAEIKSGLCVPGESVRIQRGPATRQRDGHFKKRSRPDLRTRA
RRNLYKKQESEQAGVAKDAKSVASDVPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPE
FPVESVASRIQAEPDNLARASASPDRIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKP
RLEDRQSFRNTIESVHTEKPQPTKEEPKVPPIRIQLSRIKPPWVVKGQPTYQICPRIIPT
TESSCRGWTGARTLADIKARALQVRGARGHHCHREAATTAIGGGGGPGGGGGGATDEGGG
RGSSSGDGGEACGHPEPRGGPSTPGKCTSDLQRTQLLPPYPLNGEHTQAGTAMSRARRED
LPSLRKEESCLLQRATVGLTDGLGDASQLPVAPTGDQPCQALPLLSSQTSVAERLVEQPQ
LHPDVRTECESGTTSWESDDEEQGPTVPADNGPIPSLVGDDTLEKGTGQALDSHPTMKDP
VNVTPSSTPESSPTDCLQNRAFDDELGLGGSCPPMRESDTRQENLKTKALVSNSSLHWIP
IPSNDEVVKQPKPESREHIPSVEPQVGEEWEKAAPTPPALPGDLTAEEGLDPLDSLTSLW
TVPSRGGSDSNGSYCQQVDIEKLKINGDSEALSPHGESTDTASDFEGHLTEDSSEADTRE
AAVTKGSSVDKDEKPNWNQSAPLSKVNGDMRLVTRTDGMVAPQSWVSRVCAVRQKIPDSL
LLASTEYQPRAVCLSMPGSSVEATNPLVMQLLQGSLPLEKVLPPAHDDSMSESPQVPLTK
DQSHGSLRMGSLHGLGKNSGMVDGSSPSSLRALKEPLLPDSCETGTGLARIEATQAPGAP
QKNCKAVPSFDSLHPVTNPITSSRKLEEMDSKEQFSSFSCEDQKEVRAMSQDSNSNAAPG
KSPGDLTTSRTPRFSSPNVISFGPEQTGRALGDQSNVTGQGKKLFGSGNVAATLQRPRPA
DPMPLPAEIPPVFPSGKLGPSTNSMSGGVQTPREDWAPKPHAFVGSVKNEKTFVGGPLKA
NAENRKATGHSPLELVGHLEGMPFVMDLPFWKLPREPGKGLSEPLEPSSLPSQLSIKQAF
YGKLSKLQLSSTSFNYSSSSPTFPKGLAGSVVQLSHKANFGASHSASLSLQMFTDSSTVE
SISLQCACSLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR
NT seq
4626 nt
NT seq
+upstream
nt +downstream
nt
atgaaggacaaacagaagaagaagaaggagcgcacgtgggccgaggccgcgcgcctggta
ttagaaaactactcggatgctccaatgacaccaaaacagattctgcaggtcatagaggca
gaaggactaaaggaaatgagaagtgggacttcccctctcgcatgcctcaatgctatgcta
cattccaattcaagaggaggagaggggttgttttataaactgcctggccgaatcagcctt
ttcacgctcaagaaggatgccctgcagtggtctcgccatccagctacagtggagggagag
gagccagaggacacggctgatgtggagagctgtgggtctaatgaagccagcactgtgagt
ggtgaaaacgatgtatctcttgatgaaacatcttcgaacgcatcctgttctacagaatct
cagagtcgacctctttccaatcccagggacagctacagagcttcctcacaggcgaacaaa
caaaagaaaaagactggggtgatgctgcctcgagttgtcctgactcctctgaaggtaaac
ggggcccacgtggaatctgcatcagggttctcgggctgccacgccgatggcgagagcggc
agcccgtccagcagcagcagcggctctctggccctgggcagcgctgctattcgtggccag
gccgaggtcacccaggaccctgccccgctcctgagaggcttccggaagccagccacaggt
caaatgaagcgcaacagaggggaagaaatagattttgagacacctgggtccattcttgtc
aacaccaacctccgtgccctgatcaactctcggaccttccatgccttaccatcacacttc
cagcagcagctcctcttcctcctgcctgaagtagacagacaggtggggacggatggcctg
ttgcgtctcagcagcagtgcactaaataacgagttttttacccatgcggctcagagctgg
cgggagcgcctggctgatggtgaatttactcatgagatgcaagtcaggatacgacaggaa
atggagaaggaaaagaaggtggaacaatggaaagaaaagttctttgaagactactatgga
cagaagctgggtttgaccaaagaagagtcattgcagcagaacgtgggccaggaggaggct
gaaatcaaaagtggcttgtgtgtcccaggagaatcagtgcgtatacagcgtggtccagcc
acccgacagcgagatgggcattttaagaaacgctctcggccagatctccgaaccagagcc
agaaggaatctgtacaaaaaacaggagtcagaacaagcaggggttgctaaggatgcaaaa
tctgtggcctcagatgttcccctctacaaggatggggaggctaagactgacccagcaggg
ctgagcagtccccatctgccaggcacatcctctgcagcacccgacctggagggtcccgaa
ttcccagttgagtctgtggcttctcggatccaggctgagccagacaacttggcacgtgcc
tctgcatctccagacagaattcctagcctgcctcaggaaactgtggatcaggaacccaag
gatcagaagaggaaatcctttgagcaggcggcctctgcatcctttcccgaaaagaagccc
cggcttgaagatcgtcagtcctttcgtaacacaattgaaagtgttcacaccgaaaagcca
cagcccactaaagaggagcccaaagtcccgcccatccggattcaactttcacgtatcaaa
ccaccctgggtggttaaaggtcagcccacttaccagatatgcccccggatcatccccacc
acggagtcctcctgccggggttggactggcgccaggaccctcgcagacattaaagcccgt
gctctgcaggtccgaggggcgagaggtcaccactgccatagagaggcggccaccactgcc
atcggaggggggggtggcccgggtggaggtggcggcggggccaccgatgagggaggtggc
agaggcagcagcagtggtgatggtggtgaggcctgtggccaccctgagcccaggggaggc
ccgagcacccctggaaagtgtacgtcagatctacagcgaacacaactactgccgccttat
cctctaaatggggagcatacccaggccggaactgccatgtccagagctaggagagaggac
ctgccttctctgagaaaggaggaaagctgcctactacagagggctacagttggactcaca
gatgggctaggagatgcctcccaactccccgttgctcccactggggaccagccatgccag
gccttgcccctactgtcctcccaaacctcagtagctgagagattagtggagcagcctcag
ttgcatccggatgttagaactgaatgtgagtctggcaccacttcctgggaaagtgatgat
gaggagcaaggacccaccgttcctgcagacaatggtcccattccgtctctagtgggagat
gatacattagagaaaggaactggccaagctcttgacagtcatcccactatgaaggatcct
gtaaatgtgacccccagttccacacctgaatcctcaccgactgattgcctgcagaacaga
gcatttgatgacgaattagggcttggtggctcatgccctcctatgagggaaagtgatact
agacaagaaaacttgaaaaccaaggctctcgtttctaacagttctttgcattggataccc
atcccatcgaatgatgaggtagtgaaacagcccaaaccagaatccagagaacacatacca
tctgttgagccccaggttggagaggagtgggagaaagctgctcccacccctcctgcattg
cctggggatttgacagctgaggagggtctagatcctcttgacagccttacttcactctgg
actgtgccatctcgaggaggcagtgacagcaatggcagttactgtcaacaggtggacatt
gaaaagctgaaaatcaacggagactctgaagcactgagtcctcacggtgagtccacggat
acagcctctgactttgaaggtcacctcacggaggacagcagtgaggctgacactagagaa
gctgcagtgacaaagggatcttcggtggacaaggatgagaaacccaattggaaccaatct
gccccactgtccaaggtgaatggtgacatgcgtctggttacaaggacagatgggatggtt
gctcctcagagctgggtgtctcgagtatgtgcggtccgccaaaagatcccagattcccta
ctgctggccagtactgagtaccagccaagagccgtgtgcctgtccatgcctgggtcctca
gtggaggccactaacccacttgtgatgcagttgctgcagggtagcttgcccctagagaag
gttcttccaccagcccacgatgacagcatgtcagaatccccacaagtaccacttacaaaa
gaccagagccatggctcgctacgcatgggatctttacatggtcttggaaaaaacagtggc
atggttgatggaagcagccccagttctttaagggctttgaaggagcctcttctgccagat
agctgtgaaacaggcactggtcttgccaggattgaggccacccaggctcctggagcaccc
caaaagaattgcaaggcagtcccaagttttgactccctccatccagtgacaaatcccatt
acatcctctaggaaactggaagaaatggattccaaagagcagttctcttcctttagttgt
gaagatcagaaggaagtccgtgctatgtcacaggacagtaattcaaatgctgctccagga
aagagcccaggagatcttactacctcgagaacacctcgtttctcatctccaaatgtgatc
tcctttggtccagagcagacaggtcgggccctgggtgatcagagcaatgttacaggccaa
gggaagaagctttttggctctgggaatgtggctgcaacccttcagcgccccaggcctgcg
gacccgatgcctcttcctgctgagatccctccagtttttcccagtgggaagttgggacca
agcacaaactccatgtctggtggggtacagactccaagggaagactgggctccaaagcca
catgcctttgttggcagcgtcaagaatgagaagacttttgtggggggtcctcttaaggca
aatgccgagaacaggaaagctactgggcatagtcccctggaactggtgggtcacttggaa
gggatgccctttgtcatggacttgcccttctggaaattaccccgagagccagggaagggg
ctcagtgagcctctggagccttcttctctcccctcccaactcagcatcaagcaggcattt
tatgggaagctttctaaactccaactgagttccaccagctttaattattcctctagctct
cccacctttcccaaaggccttgctggaagtgtggtgcagctgagccacaaagcaaacttt
ggtgcgagccacagtgcatcactttccttgcaaatgttcactgacagcagcacggtggaa
agcatctcgctccagtgtgcgtgcagcctgaaagccatgatcatgtgccaaggctgcggt
gcgttctgtcacgatgactgtattggaccctcaaagctctgtgtattgtgccttgtggtg
agataa
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integrated database retrieval system
