KEGG   NETWORK: N01636
Entry
N01636                      Network                                
Name
Loading of the SMC5-SMC6 complex
Definition
RNF168 -> RAD18+UBB == SLF1+SLF2 == SMC5-SMC6
  Expanded
165918 -> 56852+7314 == 84250+55719 == (23137+79677+197370+286053+56160+54780)
Class
nt06506 Double-strand break repair
Type
Reference
Gene
165918  RNF168; ring finger protein 168
56852  RAD18; RAD18 E3 ubiquitin protein ligase
7314  UBB; ubiquitin B
84250  SLF1; SMC5-SMC6 complex localization factor 1
55719  SLF2; SMC5-SMC6 complex localization factor 2
23137  SMC5; structural maintenance of chromosomes 5
79677  SMC6; structural maintenance of chromosomes 6
197370  NSMCE1; NSE1 homolog, SMC5-SMC6 complex component
286053  NSMCE2; NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
56160  NSMCE3; NSE3 homolog, SMC5-SMC6 complex component
54780  NSMCE4A; NSE4 homolog A, SMC5-SMC6 complex component
Reference
PMID:30600397
  Authors
Oravcova M, Boddy MN
  Title
Recruitment, loading, and activation of the Smc5-Smc6 SUMO ligase.
  Journal
Curr Genet 65:669-676 (2019)
DOI:10.1007/s00294-018-0922-9
Reference
PMID:25931565
  Authors
Raschle M, Smeenk G, Hansen RK, Temu T, Oka Y, Hein MY, Nagaraj N, Long DT, Walter JC, Hofmann K, Storchova Z, Cox J, Bekker-Jensen S, Mailand N, Mann M
  Title
DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links.
  Journal
Science 348:1253671 (2015)
DOI:10.1126/science.1253671
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