KEGG   Homo sapiens (human): 84250
Entry
84250             CDS       T01001                                 
Symbol
SLF1, ANKRD32, BRCTD1, BRCTx, hNSE5
Name
(RefSeq) SMC5/6 complex localization factor 1
  KO
K26126  SMC5-SMC6 complex localization factor protein 1
Organism
hsa  Homo sapiens (human)
Network
nt06506  Double-strand break repair
  Element
N01636  Loading of the SMC5-SMC6 complex
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    84250 (SLF1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    SMC5-SMC6 complex
     84250 (SLF1)
SSDB
Motif
Pfam: BRCT_TopB1_SLF1 Ank_2 Ank Ank_3 Ank_5 Ank_4 RTT107_BRCT_5
Other DBs
NCBI-GeneID: 84250
NCBI-ProteinID: NP_115666
OMIM: 618467
HGNC: 25408
Ensembl: ENSG00000133302
UniProt: Q9BQI6 I6L9F1
Structure
LinkDB
Position
5:94618231..94697621
AA seq 1058 aa
MEDGTPKHIIQMTGFKMEEKEALVKLLLKLDCTFIKSEKYKNCTHLIAERLCKSEKFLAA
CAAGKWILTKDYIIHSAKSGRWLDETTYEWGYKIEKDSRYSPQMQSAPKRWREELKRTGA
PGAFHRWKVVLLVRTDKRSDSLIRVLEAGKANVILPKSSPSGITHVIASNARIKAEKEKD
NFKAPFYPIQYLGDFLLEKEIQNDEDSQTNSVWTEHSNEETNKDFRKDAGFLEMKGALRE
TMYRTQKEMQNHEDVNVGSILIQHHKKEKFSGSSKDLKFVKMRNTFGSHTYENQKEIKKK
DEDIQRSYTLRRKRKKGKESNCKKGVEHEKIKSTLRRHIYNRDQKEMKNSIFAEYAKESK
AMAIKTDVDVVEIKNTLRKHIYRAQAVRYNCIRIDKQPVYNVEVKNAEFPRGVLNLIESL
IEGHFFKEAIEELSTLQAHYIPPVCVLHALLENVLQDNIDTFSGRYFHILSALLHLHPPW
KSPAMSRYYLELFQCPTCMKGAWSLVEVLIRSCLFNESFCHQISENIGSKVLHLTLLKFF
FNLIESEVQHLSQKLYDWSDSQNLKITGKAMLLEIFWSGSETSGLLTKPVNMLLEWTIYS
HKEKFKSNDVFKHELAYLLAGILGAAIDYWIFLGLKMGRNVMRHMSDDLGSYVSLSCDDF
SSQELEIFICSFSSSWLQMFVAEAVFKKLCLQSSGSVSSEPLSLQKMVYSYLPALGKTGV
LGSGKIQVSKKIGQRPCFDSQRTLLMLNGTKQKQVEGLPELLDLNLAKCSSSLKKLKKKS
EGELSCSKENCPSVVKKMNFHKTNLKGETALHRACINNQVEKLILLLSLPGIDINVKDNA
GWTPLHEACNYGNTVCVQEILQRCPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQHGGP
VLLQQRNAKGELPLDYVVSPQIKEELFAITKIEDTVENFHAQAEKHFHYQQLEFGSFLLS
RMLLNFCSIFDLSSEFILASKGLTHLNELLMACKSHKETTSVHTDWLLDLYAGNIKTLQK
LPHILKELPENLKVCPGVHTEALMITLEMMCRSVMEFS
NT seq 3177 nt   +upstreamnt  +downstreamnt
atggaagatggtaccccaaagcatatcatccagatgacaggatttaagatggaagaaaaa
gaagcgctagtcaaattacttttaaaactagattgcacttttattaagagtgagaaatac
aaaaattgtacacatcttatagctgaacgcctatgtaagagtgaaaaatttttagcagct
tgtgcggcaggaaagtggatactaaccaaggactatataattcatagtgccaaaagtggc
agatggcttgatgaaacaacttatgaatggggatataaaattgaaaaagattcccgttat
tcacctcaaatgcaatctgcacctaaaagatggcgtgaagaactgaaacgcactggtgct
ccaggagccttccacagatggaaagttgtcctccttgttagaactgataagcgaagtgat
tctcttataagagttttggaggctggaaaggcaaatgttattttaccaaaaagttcacca
agtggaataactcatgtgattgccagtaatgcaagaattaaagctgagaaagaaaaagat
aactttaaggctccattttatccaattcagtatctaggggattttcttttagagaaagaa
attcagaatgatgaagattcccaaaccaattctgtttggactgaacatagcaatgaagaa
acaaacaaagatttcaggaaagatgcaggatttcttgaaatgaaaggtgccttaagagag
accatgtatagaacccagaaagaaatgcaaaatcatgaagatgttaatgttggttctatt
ttgattcaacatcacaaaaaagaaaaattcagtggttccagtaaagatttgaaatttgtt
aaaatgagaaatacctttggaagccatacatatgaaaatcagaaggaaattaagaaaaaa
gatgaagatattcagaggagttatactttgaggagaaaacgcaagaaaggaaaagaaagc
aattgcaagaaaggcgttgaacatgaaaaaataaaaagtaccttaagaaggcacatatat
aatagagatcagaaagaaatgaagaattctatttttgctgaatatgccaaagaatcaaaa
gccatggctattaagacagatgtggatgttgttgaaataaaaaataccttaaggaagcac
atatatagagctcaggctgtcagatacaactgcattagaatagataaacaaccagtgtac
aacgtagaggttaaaaatgctgaatttcccagaggtgtattaaatttaattgaaagcctc
atagaaggacatttttttaaagaagcaattgaggaactttccactttgcaggcacattat
atccctcctgtatgcgttcttcatgcccttctagagaacgttctacaggataacatagat
acattttctggtcgatactttcatatattgtcagctcttcttcacctgcatcctccttgg
aagtctccagccatgtcgagatattatttagagttgtttcagtgtccaacttgtatgaaa
ggagcatggtctttagtagaagtccttatcaggtcttgccttttcaatgaaagcttttgt
catcaaatttcagaaaatattggctccaaggtgctccacctgacgctactcaaatttttc
tttaatttaattgaaagtgaagtacaacatctgagtcaaaagttgtatgactggtcagat
tctcagaatctgaaaataacaggaaaggcaatgcttcttgaaattttttggtcaggaagt
gaaacctctgggcttttgaccaaaccagtaaatatgcttttggaatggactatatattct
cacaaggaaaaattcaagtctaatgatgtcttcaaacatgaactagcttacttattggct
ggaattcttggagcagcaatagattattggattttccttggtcttaagatgggtagaaat
gtgatgcgacacatgtctgatgacttaggaagttatgtttctctttcgtgtgatgacttt
tcttcacaggaattagagattttcatttgctccttttcctcctcctggcttcaaatgttt
gttgcagaggcagtctttaaaaagttgtgtctacagagctctggcagtgtttcttctgag
ccactctctcttcagaaaatggtatattcctatttaccagccttggggaaaactggtgtg
cttgggtctggaaagattcaggtgtcaaagaaaataggacagcggccttgttttgactct
cagagaaccttactaatgctgaatggtactaaacaaaaacaagtcgaagggctgccagag
ttactagacctgaaccttgctaaatgttcctcatcattaaaaaaattgaaaaagaagtca
gaaggagaattgtcatgttccaaggagaattgcccctctgtagttaaaaagatgaatttt
cacaagactaatctaaaaggagaaacagccctgcatagagcttgcataaataaccaagtg
gagaaattgattcttcttctctctttgccaggaatagacatcaatgttaaagacaatgct
ggctggacgcctttgcatgaagcctgtaactatggcaacacagtgtgtgtccaggaaatt
ttgcaacgttgtccagaggtagatctgctcactcaagtggacggggtgactcctttgcat
gatgcactgtcaaacggacatgtagaaattggcaagctgctactacagcatgggggccca
gtgcttttacaacagaggaatgctaagggagaattgcccttggattatgtggtttcacct
caaatcaaagaagaactgtttgctattacaaaaatagaagatacagtggagaactttcat
gcacaagcagagaaacattttcattaccagcaacttgaatttggctcctttttacttagt
aggatgttgctaaatttttgttcaatttttgatttatcttcagagttcattttagcttcc
aaagggttaactcatctaaatgaactgcttatggcttgtaaaagtcataaagaaaccacc
agtgttcatactgactggttactggatctttatgctggaaatataaagacattgcagaaa
ctcccacacattcttaaggaactgcctgagaatttgaaagtgtgtcctggggtacacact
gaggccttgatgataacattggaaatgatgtgtcggtcagtcatggagttttcatga

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