| Entry |
|
| Name |
PINK-Parkin-independent ubiquitin-mediated mitophagy, ubiquitin E3 ligase
|
| Definition |
PINK1 -> PRKN -> Outer_membrane_protein |
| Expanded |
65018 -> 5071 -> (55847,493856,23197,23770,9868,3098) |
| Class |
|
| Type |
Reference
|
| Pathway |
|
| Gene |
| 65018 | PINK1; PTEN induced kinase 1 |
| 5071 | PRKN; parkin RBR E3 ubiquitin protein ligase |
| 55847 | CISD1; CDGSH iron sulfur domain 1 |
| 493856 | CISD2; CDGSH iron sulfur domain 2 |
| 23197 | FAF2; Fas associated factor family member 2 |
| 23770 | FKBP8; FKBP prolyl isomerase 8 |
| 9868 | TOMM70; translocase of outer mitochondrial membrane 70 |
|
| Reference |
|
| Authors |
Palikaras K, Lionaki E, Tavernarakis N |
| Title |
Mechanisms of mitophagy in cellular homeostasis, physiology and pathology. |
| Journal |
|
| Reference |
|
| Authors |
Yoo SM, Jung YK |
| Title |
A Molecular Approach to Mitophagy and Mitochondrial Dynamics. |
| Journal |
|
| Reference |
|
| Authors |
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW |
| Title |
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. |
| Journal |
|
| Reference |
|
| Authors |
Ordureau A, Paulo JA, Zhang W, Ahfeldt T, Zhang J, Cohn EF, Hou Z, Heo JM, Rubin LL, Sidhu SS, Gygi SP, Harper JW |
| Title |
Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics. |
| Journal |
|
| Reference |
|
| Authors |
Herhaus L, Dikic I |
| Title |
Expanding the ubiquitin code through post-translational modification. |
| Journal |
|
| LinkDB |
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