Homo sapiens (human): 23770
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Entry
23770 CDS
T01001
Symbol
FKBP8, FKBP38, FKBPr38
Name
(RefSeq) FKBP prolyl isomerase 8
KO
K09574
FK506-binding protein 8 [EC:
5.2.1.8
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04137
Mitophagy - animal
Network
nt06464
Amyotrophic lateral sclerosis
nt06466
Pathways of neurodegeneration
nt06536
Mitophagy
Element
N01137
PINK-Parkin-mediated autophagosome formation
N01138
Mutation-inactivated OPTN to PINK-Parkin-mediated autophagosome formation
N01139
Mutation-inactivated p62 to PINK-Parkin-mediated autophagosome formation
N01756
PINK-Parkin-independent ubiquitin-mediated mitophagy
N01757
PINK-Parkin-independent ubiquitin-mediated mitophagy, ubiquitin E3 ligase
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
23770 (FKBP8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
23770 (FKBP8)
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
hsa03110
]
23770 (FKBP8)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.2 cis-trans-Isomerases
5.2.1 cis-trans Isomerases (only sub-subclass identified to date)
5.2.1.8 peptidylprolyl isomerase
23770 (FKBP8)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Calcineurin (PPP3/ PP2B)
Other calcineurin-interacting proteins
23770 (FKBP8)
Chaperones and folding catalysts [BR:
hsa03110
]
Protein folding catalysts
Peptidyl prolyl isomerase
FKBP
23770 (FKBP8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FKBP_C
TPR_1
TPR_2
TPR_16
TPR_14
Fis1_TPR_C
TPR_19
TPR_11
TPR_8
TPR_9
TPR_17
ANAPC3
TPR_12
TPR_7
TPR_CcmH_CycH
TPR_6
TPR_Slam
ARM_TT21_5th
NatA_aux_su
ARM_TT21
UBL_UBAC1
Motif
Other DBs
NCBI-GeneID:
23770
NCBI-ProteinID:
NP_001295302
OMIM:
604840
HGNC:
3724
Ensembl:
ENSG00000105701
UniProt:
Q14318
B2R8G6
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:complement(18531763..18543573)
Genome browser
AA seq
412 aa
AA seq
DB search
MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ
PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG
QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG
PQGRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLA
ANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLE
HQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTE
TALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN
NT seq
1239 nt
NT seq
+upstream
nt +downstream
nt
atggcatcgtgtgctgaaccctctgagccctctgccccactgcccgccggggtcccaccg
ctcgaggacttcgaggtactggatggggttgaggatgcagagggtgaggaggaagaggag
gaggaagaggaggaagaggatgacctgagtgagctgccaccgctggaggacatgggacaa
cccccggcggaggaggctgagcagcctggggccctggcccgagagttccttgctgccatg
gagcccgagcccgccccagccccggccccagaagagtggctggacattctggggaacggg
ctgttgaggaagaagacgctggtcccagggccgccaggttcgagccgcccggtcaagggc
caggtggtcaccgtacatctgcagacgtcgctggagaatggcacacgggtgcaggaggag
ccggagctggtgttcactctgggtgactgtgacgtcatccaggccctggatctcagtgtc
ccactcatggacgtgggggagacggccatggtcactgctgactccaagtactgctacggc
ccccaaggcaggagcccatacatccccccgcacgcggccctgtgcctggaggtgaccctg
aagacggctgtggacgggcctgacctggagatgctcacggggcaggagcgcgtggccctg
gccaaccggaagcgggagtgcggcaacgcccactaccagcgggcggacttcgtcctggcc
gccaactcctacgacctcgccatcaaggctatcacctccagcgccaaagtggacatgacg
ttcgaggaggaggcacagctcctgcagttgaaggtgaagtgtctgaacaacctggcggcc
tcgcagctgaagctcgaccactaccgcgcagccctgcgctcctgcagccttgtgctggag
caccagccagacaacatcaaggctctcttccgcaagggcaaggtgctggcccagcagggg
gagtacagtgaggccatccccatcctgagggcagccctgaagctggaaccttccaacaag
acgatccacgcagagctctcaaagctggtgaagaagcatgcggcgcagcggagcacggag
accgccttgtaccggaaaatgctgggcaaccccagccggctgcctgctaagtgccctggc
aagggtgcctggtccatcccatggaagtggctgtttggggcgactgctgttgccttgggg
ggtgtggcactctctgtggtcatcgctgccaggaactga
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