| Entry |
|
| Name |
CXCR4-GNAQ-PLCB/G signaling pathway
|
| Definition |
CXCL12 -> CXCR4 -> GNAQ -> (PLCB,PLCG) |
| Expanded |
6387 -> 7852 -> 2776 -> (23236,5330,5331,5332,5335,5336) |
| Class |
|
| Type |
Reference
|
| Pathway |
|
| Gene |
| 6387 | CXCL12; C-X-C motif chemokine ligand 12 |
| 7852 | CXCR4; C-X-C motif chemokine receptor 4 |
| 2776 | GNAQ; G protein subunit alpha q |
| 23236 | PLCB1; phospholipase C beta 1 |
| 5330 | PLCB2; phospholipase C beta 2 |
| 5331 | PLCB3; phospholipase C beta 3 |
| 5332 | PLCB4; phospholipase C beta 4 |
| 5335 | PLCG1; phospholipase C gamma 1 |
| 5336 | PLCG2; phospholipase C gamma 2 |
|
| Reference |
|
| Authors |
Wu Y, Yoder A |
| Title |
Chemokine coreceptor signaling in HIV-1 infection and pathogenesis. |
| Journal |
|
| Reference |
|
| Authors |
Knopf A, Fritsche MK, Li Y |
| Title |
CXCR4: A New Player in an Old Scene? |
| Journal |
|
| Reference |
|
| Authors |
Scala S |
| Title |
Molecular Pathways: Targeting the CXCR4-CXCL12 Axis--Untapped Potential in the Tumor Microenvironment. |
| Journal |
|
| Reference |
|
| Authors |
Barbieri F, Bajetto A, Florio T |
| Title |
Role of chemokine network in the development and progression of ovarian cancer: a potential novel pharmacological target. |
| Journal |
|
| LinkDB |
|