KEGG   NETWORK: N01785
Entry
N01785                      Network                                
Name
Don't eat me signal (CD47)
Definition
CD47 -> SIRPA -> SHP1,SHP2
  Expanded
961 -> 140885 -> 5777,5778
Class
nt06535 Efferocytosis
Type
Reference
Pathway
hsa04148 Efferocytosis   
Gene
961  CD47; CD47 molecule
140885  SIRPA; signal regulatory protein alpha
5777  PTPN6; protein tyrosine phosphatase non-receptor type 6
5778  PTPN7; protein tyrosine phosphatase non-receptor type 7
Reference
PMID:32251387
  Authors
Boada-Romero E, Martinez J, Heckmann BL, Green DR
  Title
The clearance of dead cells by efferocytosis.
  Journal
Nat Rev Mol Cell Biol 21:398-414 (2020)
DOI:10.1038/s41580-020-0232-1
Reference
PMID:33597922
  Authors
Wang L, Li H, Tang Y, Yao P
  Title
Potential Mechanisms and Effects of Efferocytosis in Atherosclerosis.
  Journal
Front Endocrinol (Lausanne) 11:585285 (2020)
DOI:10.3389/fendo.2020.585285
Reference
PMID:28606940
  Authors
Abram CL, Lowell CA
  Title
Shp1 function in myeloid cells.
  Journal
J Leukoc Biol 102:657-675 (2017)
DOI:10.1189/jlb.2MR0317-105R
Reference
PMID:36626230
  Authors
Li Y, Zhou H, Liu P, Lv D, Shi Y, Tang B, Xu J, Zhong T, Xu W, Zhang J, Zhou J, Ying K, Zhao Y, Sun Y, Jiang Z, Cheng H, Zhang X, Ke Y
  Title
SHP2 deneddylation mediates tumor immunosuppression in colon cancer via the CD47/SIRPalpha axis.
  Journal
J Clin Invest 133:162870 (2023)
DOI:10.1172/JCI162870
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