KEGG   NETWORK: N01898
Entry
N01898                      Network                                
Name
Dopamine-DRD-GNAI/O signaling pathway
Definition
Dopamine -> DRD -> (GNAI,GNAO) -| ADCY5
  Expanded
C03758 -> (1813,1814,1815) -> ((2770,2771,2773),2775) -| 111
Class
nt06544 Neuroactive ligand signaling
Type
Reference
Pathway
hsa04728  Dopaminergic synapse
hsa04082  Neuroactive ligand signaling
Gene
1813  DRD2; dopamine receptor D2
1814  DRD3; dopamine receptor D3
1815  DRD4; dopamine receptor D4
2770  GNAI1; G protein subunit alpha i1
2771  GNAI2; G protein subunit alpha i2
2773  GNAI3; G protein subunit alpha i3
2775  GNAO1; G protein subunit alpha o1
111  ADCY5; adenylate cyclase 5
Metabolite
C03758  Dopamine
Reference
PMID:36757901
  Authors
Channer B, Matt SM, Nickoloff-Bybel EA, Pappa V, Agarwal Y, Wickman J, Gaskill PJ
  Title
Dopamine, Immunity, and Disease.
  Journal
Pharmacol Rev 75:62-158 (2023)
DOI:10.1124/pharmrev.122.000618
Reference
PMID:30446950
  Authors
Klein MO, Battagello DS, Cardoso AR, Hauser DN, Bittencourt JC, Correa RG
  Title
Dopamine: Functions, Signaling, and Association with Neurological Diseases.
  Journal
Cell Mol Neurobiol 39:31-59 (2019)
DOI:10.1007/s10571-018-0632-3
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