Homo sapiens (human): 1815
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Entry
1815 CDS
T01001
Symbol
DRD4, D4DR
Name
(RefSeq) dopamine receptor D4
KO
K04147
dopamine receptor D4
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04081
Hormone signaling
hsa04082
Neuroactive ligand signaling
hsa04728
Dopaminergic synapse
Network
nt06544
Neuroactive ligand signaling
Element
N01898
Dopamine-DRD-GNAI/O signaling pathway
Disease
H01895
Attention deficit hyperactivity disorder (ADHD)
Drug target
Clozapine:
D00283
<JP/US>
Dexpramipexole (
DG01331
):
D09886
D09887
Dopamine (
DG00213
):
D00633
<JP/US>
D07870
Dopexamine (
DG00222
):
D03891
D03892
Etilevodopa:
D04097
Fananserin:
D02656
Foslevodopa:
D11839
Levodopa:
D00059
<JP/US>
Lisuride (
DG00453
):
D01462
D08132
Olanzapine (
DG00898
):
D00454
<JP/US>
D06623
<US>
Oxiperomide:
D02676
Pramipexole (
DG00863
):
D00559
<JP/US>
D05575
Ropinirole (
DG00862
):
D00784
<JP/US>
D08489
Sonepiprazole mesylate:
D05891
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
1815 (DRD4)
04082 Neuroactive ligand signaling
1815 (DRD4)
04081 Hormone signaling
1815 (DRD4)
09150 Organismal Systems
09156 Nervous system
04728 Dopaminergic synapse
1815 (DRD4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
1815 (DRD4)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Biogenic amine
Dopamine
1815 (DRD4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
7TM_GPCR_Srsx
7tm_4
7TM_GPCR_Srx
Motif
Other DBs
NCBI-GeneID:
1815
NCBI-ProteinID:
NP_000788
OMIM:
126452
HGNC:
3025
Ensembl:
ENSG00000069696
UniProt:
P21917
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:637269..640706
Genome browser
AA seq
419 aa
AA seq
DB search
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
NT seq
1260 nt
NT seq
+upstream
nt +downstream
nt
atggggaaccgcagcaccgcggacgcggacgggctgctggctgggcgcgggccggccgcg
ggggcatctgcgggggcatctgcggggctggctgggcagggcgcggcggcgctggtgggg
ggcgtgctgctcatcggcgcggtgctcgcggggaactcgctcgtgtgcgtgagcgtggcc
accgagcgcgccctgcagacgcccaccaactccttcatcgtgagcctggcggccgccgac
ctcctcctcgctctcctggtgctgccgctcttcgtctactccgaggtccagggtggcgcg
tggctgctgagcccccgcctgtgcgacgccctcatggccatggacgtcatgctgtgcacc
gcctccatcttcaacctgtgcgccatcagcgtggacaggttcgtggccgtggccgtgccg
ctgcgctacaaccggcagggtgggagccgccggcagctgctgctcatcggcgccacgtgg
ctgctgtccgcggcggtggcggcgcccgtactgtgcggcctcaacgacgtgcgcggccgc
gaccccgccgtgtgccgcctggaggaccgcgactacgtggtctactcgtccgtgtgctcc
ttcttcctaccctgcccgctcatgctgctgctctactgggccacgttccgcggcctgcag
cgctgggaggtggcacgtcgcgccaagctgcacggccgcgcgccccgccgacccagcggc
cctggcccgccttcccccacgccacccgcgccccgcctcccccaggacccctgcggcccc
gactgtgcgccccccgcgcccggccttccccggggtccctgcggccccgactgtgcgccc
gccgcgcccagcctcccccaggacccctgcggccccgactgtgcgccccccgcgcccggc
ctccccccggacccctgcggctccaactgtgctccccccgacgccgtcagagccgccgcg
ctcccaccccagactccaccgcagacccgcaggaggcggcgtgccaagatcaccggccgg
gagcgcaaggccatgagggtcctgccggtggtggtcggggccttcctgctgtgctggacg
cccttcttcgtggtgcacatcacgcaggcgctgtgtcctgcctgctccgtgcccccgcgg
ctggtcagcgccgtcacctggctgggctacgtcaacagcgccctcaaccccgtcatctac
actgtcttcaacgccgagttccgcaacgtcttccgcaaggccctgcgtgcctgctgctga
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