 | | NETWORK: N01908 | |
| Entry |
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| Name |
ADP/UDP-glucose-P2RY-GNAI/O signaling pathway
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| Definition |
(ADP,UDP-glucose) -> P2RY12/13/14 -> (GNAI,GNAO) -| ADCY |
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| Expanded |
(C00008,C00029) -> (64805,53829,9934) -> ((2770,2771,2773),2775) -| (107,108,109,196883,111,112,113,114,115) |
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| Class |
nt06544 Neuroactive ligand signaling
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| Type |
Reference
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| Pathway |
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| Gene |
| 64805 | P2RY12; purinergic receptor P2Y12 |
| 53829 | P2RY13; purinergic receptor P2Y13 |
| 9934 | P2RY14; purinergic receptor P2Y14 |
| 2770 | GNAI1; G protein subunit alpha i1 |
| 2771 | GNAI2; G protein subunit alpha i2 |
| 2773 | GNAI3; G protein subunit alpha i3 |
| 2775 | GNAO1; G protein subunit alpha o1 |
| 107 | ADCY1; adenylate cyclase 1 |
| 108 | ADCY2; adenylate cyclase 2 |
| 109 | ADCY3; adenylate cyclase 3 |
| 196883 | ADCY4; adenylate cyclase 4 |
| 111 | ADCY5; adenylate cyclase 5 |
| 112 | ADCY6; adenylate cyclase 6 |
| 113 | ADCY7; adenylate cyclase 7 |
| 114 | ADCY8; adenylate cyclase 8 |
| 115 | ADCY9; adenylate cyclase 9 |
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| Metabolite |
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| Reference |
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| Authors |
Rassendren F, Audinat E |
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| Title |
Purinergic signaling in epilepsy. |
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| Journal |
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| Reference |
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| Authors |
Fischer W, Krugel U |
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| Title |
P2Y receptors: focus on structural, pharmacological and functional aspects in the brain. |
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| Journal |
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| Reference |
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| Authors |
Huang Z, Xie N, Illes P, Di Virgilio F, Ulrich H, Semyanov A, Verkhratsky A, Sperlagh B, Yu SG, Huang C, Tang Y |
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| Title |
From purines to purinergic signalling: molecular functions and human diseases. |
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| Journal |
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| LinkDB |
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