| Entry |
|
|---|
| Name |
Histamine metabolism and transport in neuron
|
|---|
| Definition |
Histidine -- HDC -> Histamine(cyto) -- VMAT2 -> Histamine(vesicular) -> Histamine(extracellular) -- (SLC22A3,SLC29A4) -> Histamine(cyto) -- HNMT -> N-Methylhistamine |
|---|
| Expanded |
C00135 -- 3067 -> C00388 -- 6571 -> C00388 -> C00388 -- (6581,222962) -> C00388 -- 3176 -> C05127 |
|---|
| Class |
nt06544 Neuroactive ligand signaling
|
|---|
| Type |
Reference
|
|---|
| Gene |
| 3067 | HDC; histidine decarboxylase |
| 6571 | SLC18A2; solute carrier family 18 member A2 |
| 6581 | SLC22A3; solute carrier family 22 member 3 |
| 222962 | SLC29A4; solute carrier family 29 member 4 |
| 3176 | HNMT; histamine N-methyltransferase |
|
|---|
| Metabolite |
|
|---|
| Reference |
|
|---|
| Authors |
Schneider EH, Neumann D, Seifert R |
|---|
| Title |
Modulation of behavior by the histaminergic system: lessons from HDC-, H3R- and H4R-deficient mice. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Yoshikawa T, Naganuma F, Iida T, Nakamura T, Harada R, Mohsen AS, Kasajima A, Sasano H, Yanai K |
|---|
| Title |
Molecular mechanism of histamine clearance by primary human astrocytes. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Szukiewicz D |
|---|
| Title |
Histaminergic System Activity in the Central Nervous System: The Role in Neurodevelopmental and Neurodegenerative Disorders. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
