Homo sapiens (human): 3067
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Entry
3067 CDS
T01001
Symbol
HDC
Name
(RefSeq) histidine decarboxylase
KO
K01590
histidine decarboxylase [EC:
4.1.1.22
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00340
Histidine metabolism
hsa01100
Metabolic pathways
Network
nt06037
Histidine metabolism
nt06544
Neuroactive ligand signaling
Element
N01729
Histamine biosynthesis
N01912
Histamine metabolism and transport in neuron
Disease
H00862
Tourette syndrome
Drug target
Brocresine:
D03158
Tritoqualine:
D07405
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
3067 (HDC)
Enzymes [BR:
hsa01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.22 histidine decarboxylase
3067 (HDC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pyridoxal_deC
Aminotran_1_2
Beta_elim_lyase
Motif
Other DBs
NCBI-GeneID:
3067
NCBI-ProteinID:
NP_002103
OMIM:
142704
HGNC:
4855
Ensembl:
ENSG00000140287
UniProt:
P19113
Structure
PDB
PDBj
LinkDB
All DBs
Position
15:complement(50241947..50265726)
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AA seq
662 aa
AA seq
DB search
MMEPEEYRERGREMVDYICQYLSTVRERRVTPDVQPGYLRAQLPESAPEDPDSWDSIFGD
IERIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVM
DWLAKMLGLPEHFLHHHPSSQGGGVLQSTVSESTLIALLAARKNKILEMKTSEPDADESC
LNARLVAYASDQAHSSVEKAGLISLVKMKFLPVDDNFSLRGEALQKAIEEDKQRGLVPVF
VCATLGTTGVCAFDCLSELGPICAREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFT
FNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVATDFMHWQIPLSRRFRSV
KLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRNDPSFEIPAKRHLGLVVFRLKGPNCLT
ENVLKEIAKAGRLFLIPATIQDKLIIRFTVTSQFTTRDDILRDWNLIRDAATLILSQHCT
SQPSPRVGNLISQIRGARAWACGTSLQSVSGAGDDPVQARKIIKQPQRVGAGPMKRENGL
HLETLLDPVDDCFSEEAPDATKHKLSSFLFSYLSVQTKKKTVRSLSCNSVPVSAQKPLPT
EASVKNGGSSRVRIFSRFPEDMMMLKKSAFKKLIKFYSVPSFPECSSQCGLQLPCCPLQA
MV
NT seq
1989 nt
NT seq
+upstream
nt +downstream
nt
atgatggagcctgaggagtacagagagagagggagagagatggtggattacatctgccag
tacctgagcactgtgcgggagagacgtgtgacgccagacgtgcagcctggctacctgcga
gcccagctgcctgagagtgctcctgaggaccccgacagctgggacagcatctttggggac
attgaacgaatcatcatgcctggggtggtacattggcagagcccccatatgcacgcctac
tacccagccctcacctcttggccctccctgctaggagacatgctggctgatgccatcaac
tgcttgggattcacctgggcatccagccctgcgtgtacagagctggagatgaacgtcatg
gactggttggcaaaaatgctgggacttccagagcacttcttgcaccaccaccccagcagc
cagggcggaggcgtcctgcagagcacggtcagtgaatccactttgattgccctgctggca
gcaaggaagaacaaaatcctggaaatgaaaacgtctgagcccgatgctgatgagtcctgc
ctaaatgcccgactcgtggcctatgcctctgaccaggctcactcctctgtggaaaaggct
ggtttgatttcccttgtgaagatgaaatttctgcctgtggatgacaacttctcactccga
ggggaagctcttcagaaggccatcgaggaagacaagcagcggggcttggtgcccgtcttt
gtctgtgcaacactagggaccactggggtctgtgcatttgactgcctgtcagagctgggc
cccatctgtgcccgtgaggggctgtggctccacatcgatgctgcttatgcaggcactgcc
ttcctgtgccccgagttccgggggtttctgaaggggattgagtatgccgactccttcacc
tttaatccttccaagtggatgatggtgcattttgactgtactgggttctgggtcaaggac
aagtacaagctgcagcagaccttcagtgtgaatcccatctacctcaggcatgccaactca
ggcgtggccaccgacttcatgcactggcagatccccctgagccgacggtttcgctctgtt
aaactctggttcgtgattcggtccttcggggtgaagaatcttcaagcacatgtcagacat
ggtactgaaatggctaaatattttgaatctctggtcagaaacgacccttcctttgaaatt
cctgccaagaggcaccttggcctggtggtttttcgtctaaagggtcctaattgtctcaca
gaaaatgtgttaaaggaaatagctaaagctggccgtctcttcctcatcccggccactatc
caggacaagttaatcatccgtttcactgtgacatcccagtttaccactagggatgacatc
ctgagagactggaatctcattcgagatgctgccactctcatcctgagtcagcactgtact
tcccaacccagccctcgggttgggaacctcatctcccaaatcaggggtgccagagcctgg
gcctgtggaacgtcccttcagtctgtcagtggggcaggagatgatccagtccaggccagg
aagatcatcaagcagcctcagcgtgtgggagccggtcccatgaaaagggaaaatggcctc
catcttgaaaccctgctggacccagttgatgactgcttttcagaagaggccccagatgcc
accaagcacaagctgtcctccttcctgttcagttacttgtctgtgcagactaagaagaag
acggtgcgctccctcagttgcaacagtgtgccagtgagtgctcagaagccactgcccaca
gaggcctctgtgaagaatgggggctcctccagggtcagaatcttttccaggtttccagaa
gacatgatgatgctgaagaaaagtgccttcaaaaaactcatcaaattctacagcgtcccc
agctttcctgaatgcagctctcaatgtggactccagctgccctgttgccctctgcaggcc
atggtttag
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