 | | NETWORK: N01985 | |
| Entry |
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| Name |
Integrin alphaVbeta6 signaling
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| Definition |
(FN1,TN,DSP,LAP) -> ITGAV+ITGB6 -> (Adaptor,FAK,Src) |
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| Expanded |
(2335,(3371,63923,7143,7148),1834,7040) -> 3685+3694 -> (((2316,2317),(7094,83660),(81,87),5829,7414,(55612,10979,83706),(55742,29780,64098),(3987,55679)),5747,6714) |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 1834 | DSPP; dentin sialophosphoprotein |
| 7040 | TGFB1; transforming growth factor beta 1 |
| 3685 | ITGAV; integrin subunit alpha V |
| 3694 | ITGB6; integrin subunit beta 6 |
| 81 | ACTN4; actinin alpha 4 |
| 87 | ACTN1; actinin alpha 1 |
| 55612 | FERMT1; FERM domain containing kindlin 1 |
| 10979 | FERMT2; FERM domain containing kindlin 2 |
| 83706 | FERMT3; FERM domain containing kindlin 3 |
| 55742 | PARVA; parvin alpha |
| 64098 | PARVG; parvin gamma |
| 3987 | LIMS1; LIM zinc finger domain containing 1 |
| 55679 | LIMS2; LIM zinc finger domain containing 2 |
| 5747 | PTK2; protein tyrosine kinase 2 |
| 6714 | SRC; SRC proto-oncogene, non-receptor tyrosine kinase |
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| Reference |
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| Authors |
Goodman SL, Picard M |
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| Title |
Integrins as therapeutic targets. |
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| Journal |
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| Reference |
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| Authors |
Takada Y, Ye X, Simon S |
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| Title |
The integrins. |
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| Journal |
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| Reference |
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| Authors |
Pang X, He X, Qiu Z, Zhang H, Xie R, Liu Z, Gu Y, Zhao N, Xiang Q, Cui Y |
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| Title |
Targeting integrin pathways: mechanisms and advances in therapy. |
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| Journal |
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| Reference |
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| Authors |
Wan C, Yuan G, Luo D, Zhang L, Lin H, Liu H, Chen L, Yang G, Chen S, Chen Z |
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| Title |
The Dentin Sialoprotein (DSP) Domain Regulates Dental Mesenchymal Cell Differentiation through a Novel Surface Receptor. |
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| Journal |
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| LinkDB |
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