| Entry |
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| Symbol |
PXN
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| Name |
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| KO |
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| Organism |
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| Pathway |
| hsa04670 | Leukocyte transendothelial migration |
| hsa04810 | Regulation of actin cytoskeleton |
| hsa05100 | Bacterial invasion of epithelial cells |
| hsa05163 | Human cytomegalovirus infection |
| hsa05170 | Human immunodeficiency virus 1 infection |
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| Network |
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| Element |
| N00413 | CXCR4-GNB/G-PLCB-PKC signaling pathway |
| N01068 | ITGA/B-FAK-RAC signaling pathway |
| N01070 | ITGA/B-FAK-CDC42 signaling pathway |
| N01080 | ITGA/B-TALIN/VINCULIN signaling pathway |
| N01081 | Shigella IpaB/C/D to ITGA/B-TALIN/VINCULIN signaling pathway |
| N01083 | Shigella OspE to ITGA/B-TALIN/VINCULIN signaling pathway |
| N01109 | Yersinia YopH to ITGA/B-FAK-RAC signaling pathway |
| N01921 | Integrin alpha4beta1 signaling |
| N01945 | SLIT-ROBO signaling in angiogenesis |
| N01973 | Integrin alpha4beta7 signaling |
| N01974 | Integrin alpha9beta1 signaling |
| N01975 | Integrin alphaLbeta2 signaling |
| N01976 | Integrin alphaMbeta2 signaling |
| N01977 | Integrin alphaDbeta2 signaling |
| N01978 | Integrin alphaEbeta2 signaling |
| N01979 | Integrin alphaIIbbeta3 signaling |
| N01980 | Integrin alpha5beta1 signaling |
| N01981 | Integrin alpha8beta1 signaling |
| N01982 | Integrin alphaVbeta1 signaling |
| N01983 | Integrin alphaVbeta3 signaling |
| N01984 | Integrin alphaVbeta5 signaling |
| N01985 | Integrin alphaVbeta6 signaling |
| N01986 | Integrin alphaVbeta8 signaling |
| N01987 | Integrin alpha1beta1 signaling |
| N01988 | Integrin alpha2beta1 signaling |
| N01989 | Integrin alpha10beta1 signaling |
| N01990 | Integrin alpha3beta1 signaling |
| N01991 | Integrin alpha6beta1 signaling |
| N01992 | Integrin alpha6beta4 signaling |
| N01996 | Integrin alpha11beta1 signaling |
| N01997 | Integrin alpha7beta1 signaling |
| N01998 | Integrin alphaXbeta2 signaling |
|
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
5829 (PXN)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
5829 (PXN)
04518 Integrin signaling
5829 (PXN)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
5829 (PXN)
09142 Cell motility
04810 Regulation of actin cytoskeleton
5829 (PXN)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
5829 (PXN)
04062 Chemokine signaling pathway
5829 (PXN)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
5829 (PXN)
05203 Viral carcinogenesis
5829 (PXN)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
5829 (PXN)
05163 Human cytomegalovirus infection
5829 (PXN)
05165 Human papillomavirus infection
5829 (PXN)
09171 Infectious disease: bacterial
05131 Shigellosis
5829 (PXN)
05135 Yersinia infection
5829 (PXN)
05100 Bacterial invasion of epithelial cells
5829 (PXN)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:hsa04990]
5829 (PXN)
Domain-containing proteins not elsewhere classified [BR:hsa04990]
LIM domain-containing proteins
Paxillin family proteins
5829 (PXN)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
12:complement(120210447..120265730)
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| AA seq |
591 aa
MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNG
TILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSF
PNKQKSAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGALSPL
YGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQG
EMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKIQGLEQRADGERCWAAGWPRDGG
RSSPGGQDEGGFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGA
CKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYC
NGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCA
RAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQK
PITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC |
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| NT seq |
1776 nt +upstreamnt +downstreamnt
atggacgacctcgacgccctgctggcggacttggagtctaccacctcccacatctccaaa
cggcctgtgttcttgtcggaggagaccccctactcatacccaactggaaaccacacatac
caggagattgccgtgccaccccccgtccccccacccccgtccagcgaggccctcaatggc
acaatccttgaccccttagaccagtggcagcccagcagctcccgattcatccaccagcag
cctcagtcctcatcacctgtgtacggctccagtgccaaaacttccagtgtctccaaccct
caggacagtgttggctctccgtgctcccgagtgggtgaggaggagcacgtctacagcttc
cccaacaagcagaaatcagctgagccttcacccaccgtaatgagcacgtccctgggcagc
aacctttctgaactcgaccgcctgctgctggaactgaacgctgtacagcataacccgcca
ggcttccctgcagatgaggccaactcaagccccccgcttcctggggccctgagccccctc
tatggtgtcccagagactaacagccccttgggaggcaaagctgggcccctgacgaaagag
aagcctaagcggaatgggggccggggcctggaggacgtgcggcccagtgtggagagtctc
ttggatgaactggagagctccgtgcccagccccgtccctgccatcactgtgaaccagggc
gagatgagcagcccgcagcgcgtcacctccacccaacagcagacacgcatctcggcctcc
tctgccaccagggagctggacgagctgatggcttcgctgtcggatttcaagatccagggc
ctggagcaaagagcggatggggagcggtgctgggcggccggctggcctcgggacggcggg
cggagcagccccggagggcaggacgagggagggttcatggcccaggggaagacagggagc
agctcaccccctggggggcccccgaagcccgggagccagctggacagcatgctggggagc
ctgcagtctgacctgaacaagctgggggtcgccacagtcgccaaaggagtctgcggggcc
tgcaagaagcccatcgccgggcaggttgtgaccgccatggggaagacgtggcaccccgag
cacttcgtctgcacccactgccaggaggagatcggatcccggaacttcttcgagcgggat
ggacagccctactgtgaaaaggactaccacaacctcttctccccgcgctgctactactgc
aacggccccatcctggataaagtggtgacagcccttgaccggacgtggcaccctgaacac
ttcttctgtgcacagtgtggagccttctttggtcccgaagggttccacgagaaggacggc
aaggcctactgtcgcaaggactacttcgacatgttcgcacccaagtgtggcggctgcgcc
cgggccatcctggagaactatatctcagccctcaacacgctgtggcatcctgagtgcttt
gtgtgccgggaatgcttcacgccattcgtgaacggcagcttcttcgagcacgacgggcag
ccctactgtgaggtgcactaccacgagcggcgcggctcgctgtgttctggctgccagaag
cccatcaccggccgctgcatcaccgccatggccaagaagttccaccccgagcacttcgtc
tgtgccttctgcctcaagcagctcaacaagggcaccttcaaggagcagaacgacaagcct
tactgtcagaactgcttcctcaagctcttctgctag |
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