KEGG   NETWORK: N02009
Entry
N02009                      Network                                
Name
Desmosomal cadherin to Wint signaling pathway
Definition
DSC/DSG == DSC/DSG // JUP -| CTNNB -> (TCF/LEF+CBP)
  Expanded
((1823,1824,1825),(1828,1829,1830,147409)) == ((1823,1824,1825),(1828,1829,1830,147409)) // 3728 -| 1499 -> ((6932,83439,6934,51176)+(1387,2033))
Class
nt06549 Cadherin signaling
Type
Reference
Pathway
hsa04519 Cadherin signaling   
Gene
1823  DSC1; desmocollin 1
1824  DSC2; desmocollin 2
1825  DSC3; desmocollin 3
1828  DSG1; desmoglein 1
1829  DSG2; desmoglein 2
1830  DSG3; desmoglein 3
147409  DSG4; desmoglein 4
3728  JUP; junction plakoglobin
1499  CTNNB1; catenin beta 1
6932  TCF7; transcription factor 7
83439  TCF7L1; transcription factor 7 like 1
6934  TCF7L2; transcription factor 7 like 2
51176  LEF1; lymphoid enhancer binding factor 1
1387  CREBBP; CREB binding lysine acetyltransferase
2033  EP300; EP300 lysine acetyltransferase
Reference
PMID:28703223
  Authors
Moncayo-Arlandi J, Brugada R
  Title
Unmasking the molecular link between arrhythmogenic cardiomyopathy and Brugada syndrome.
  Journal
Nat Rev Cardiol 14:744-756 (2017)
DOI:10.1038/nrcardio.2017.103
Reference
PMID:34631720
  Authors
Muller L, Hatzfeld M, Keil R
  Title
Desmosomes as Signaling Hubs in the Regulation of Cell Behavior.
  Journal
Front Cell Dev Biol 9:745670 (2021)
DOI:10.3389/fcell.2021.745670
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