Homo sapiens (human): 83439
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Entry
83439 CDS
T01001
Symbol
TCF7L1, TCF-3, TCF3
Name
(RefSeq) transcription factor 7 like 1
KO
K04490
transcription factor 7-like 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04310
Wnt signaling pathway
hsa04390
Hippo signaling pathway
hsa04520
Adherens junction
hsa04916
Melanogenesis
hsa04934
Cushing syndrome
hsa04936
Alcoholic liver disease
hsa05132
Salmonella infection
hsa05165
Human papillomavirus infection
hsa05167
Kaposi sarcoma-associated herpesvirus infection
hsa05200
Pathways in cancer
hsa05210
Colorectal cancer
hsa05213
Endometrial cancer
hsa05215
Prostate cancer
hsa05216
Thyroid cancer
hsa05217
Basal cell carcinoma
hsa05221
Acute myeloid leukemia
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
hsa05412
Arrhythmogenic right ventricular cardiomyopathy
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181
Salmonella
nt06215
WNT signaling (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06263
Hepatocellular carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06274
Thyroid cancer
nt06505
WNT signaling
Element
N00056
Wnt signaling pathway
N00057
Mutation-inactivated APC to Wnt signaling pathway
N00058
Mutation-activated CTNNB1 to Wnt signaling pathway
N00059
FZD7-overexpression to Wnt signaling pathway
N00060
LRP6-overexpression to Wnt signaling pathway
N00061
CDH1-reduced expression to beta-catenin signaling pathway
N00175
KSHV LANA to Wnt signaling pathway
N00242
Mutation-inactivated AXIN to Wnt signaling pathway
N00257
Loss of CDH1 to beta-catenin signaling pathway
N00258
Mutation-inactivated CDH1 to beta-catenin signaling pathway
N01124
Salmonella AvrA to beta-catenin signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
83439 (TCF7L1)
04390 Hippo signaling pathway
83439 (TCF7L1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
83439 (TCF7L1)
09150 Organismal Systems
09152 Endocrine system
04916 Melanogenesis
83439 (TCF7L1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
83439 (TCF7L1)
09162 Cancer: specific types
05210 Colorectal cancer
83439 (TCF7L1)
05225 Hepatocellular carcinoma
83439 (TCF7L1)
05226 Gastric cancer
83439 (TCF7L1)
05216 Thyroid cancer
83439 (TCF7L1)
05221 Acute myeloid leukemia
83439 (TCF7L1)
05217 Basal cell carcinoma
83439 (TCF7L1)
05215 Prostate cancer
83439 (TCF7L1)
05213 Endometrial cancer
83439 (TCF7L1)
05224 Breast cancer
83439 (TCF7L1)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
83439 (TCF7L1)
05165 Human papillomavirus infection
83439 (TCF7L1)
09171 Infectious disease: bacterial
05132 Salmonella infection
83439 (TCF7L1)
09166 Cardiovascular disease
05412 Arrhythmogenic right ventricular cardiomyopathy
83439 (TCF7L1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
83439 (TCF7L1)
04934 Cushing syndrome
83439 (TCF7L1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
83439 (TCF7L1)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
beta-Scaffold factors with minor groove contacts
HMG TCF-1
83439 (TCF7L1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CTNNB1_binding
HMG_box
HMG_box_2
DDAH_eukar
Motif
Other DBs
NCBI-GeneID:
83439
NCBI-ProteinID:
NP_112573
OMIM:
604652
HGNC:
11640
Ensembl:
ENSG00000152284
Pharos:
Q9HCS4
(Tbio)
UniProt:
Q9HCS4
LinkDB
All DBs
Position
2:85133392..85310387
Genome browser
AA seq
588 aa
AA seq
DB search
MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSASAQR
DLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSAFFKGPPYP
GYPFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVP
VVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPLSPGA
VGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVAPAHPGL
PTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAFMLYMKEM
RAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTWSARDNYG
KKKKRKREKQLSQTQSQQQVQEAEGALASKSKKPCVQYLPPEKPCDSPASSHGSMLDSPA
TPSAALASPAAPAATHSEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQPP
LLSRPLPLGSMPTALLASPPSFPATLHAHQALPVLQAQPLSLVTKSAH
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgccccagctcggcggcgggggcggcggcggcggcggcggcagcgggggaggcggcggc
tccagcgccggggcggccggcggaggggacgacctcggggcgaacgacgagctgatcccc
ttccaggacgaggggggcgaggagcaggagccgagcagcgatagcgcctcggcgcagcgg
gacctagacgaggtcaagtcgtccctggtcaacgagtcggagaaccagagcagcagctcg
gactcggaggcggagaggcgcccgcagcccgtccgggacactttccagaagccgcgggac
tatttcgccgaagtgagaaggcctcaggacagcgcgttctttaaaggacccccgtaccct
gggtaccccttcctgatgatcccggacctgagcagcccgtacctctccaacggacccctg
tctcccggaggagcgcgcacctacctgcagatgaaatggcccctcctcgatgtcccctcc
agcgccacagtcaaggacacgaggtcaccatctccagcacacttgtctaataaagttcct
gtcgttcagcacccgcatcacatgcatccgctgactcccctcatcacctacagcaatgac
cacttctcccccggctcccctcccacccacctctccccagagatcgatccaaagacagga
atcccccggccccctcacccatccgagctgtcaccgtattacccactctctcccggagct
gtcggacaaatcccccaccccctcggctggctcgtcccacagcaaggccagcccatgtac
tcccttcctcccggtggcttccggcacccttaccccgccctcgccatgaacgcctcgatg
tccagcctggtctccagtcggttctctcctcacatggtggctcctgcccaccctggcctg
cccacctcagggatcccccaccctgccatcgtctcccccatcgtcaagcaggaaccggca
ccccccagcctgagccctgcagtgagcgtgaaatcaccagtcaccgtgaaaaaggaggag
gaaaagaagccccacgtgaagaagcctctgaatgccttcatgttgtatatgaaggagatg
agggccaaggtggtggctgagtgcaccctgaaggaaagtgcagccattaaccagatcctt
ggaagaaagtggcacaacctgtctcgagaagaacaggccaagtactacgagctggcccgg
aaggagcggcagcttcactcgcagctctacccaacctggtcagcccgggacaactatggt
aagaaaaagaagaggaagagagaaaagcagctgtcccagacacagtcacagcagcaagtc
caggaggcagagggtgccctggcctccaagagcaagaagccatgtgttcagtacctgccc
cccgagaagccctgtgacagccctgcctcctcccacgggagcatgctggactccccggcc
actccctctgcagctttggcctcaccagctgcccctgctgccacccattcggagcaagcc
cagcccctctccctcaccaccaaaccagaaacccgggcccagctggctctccactctgcc
gccttcctgtcggctaaggctgcagcctcctcctctgggcagatgggcagccagcctccc
ctcctgtcccggcccctcccccttgggtccatgcccacagctctgctggcctctcccccg
tccttccccgccacgctccatgcccaccaggccctcccggtgctacaggcccagcctctt
tccctggtcaccaagtctgcccactaa
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