REACTION: R00256
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Entry
R00256 Reaction
Name
L-glutamine amidohydrolase
Definition
L-Glutamine + H2O <=> L-Glutamate + Ammonia
Equation
C00064
+
C00001
<=>
C00025
+
C00014
Comment
the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor
ec
6.3.5.4
(see
R00578, R00256+R00483
)
ec
6.3.5.5
(see
R00575, R00256+R10948+R10949+R01395
)
Reaction class
RC00010
C00025_C00064
RC02798
C00014_C00064
Enzyme
1.4.1.13
1.4.1.14
1.4.7.1
3.5.1.2
3.5.1.38
4.3.2.10
4.3.3.6
6.3.4.2
6.3.5.2
6.3.5.4
6.3.5.5
6.3.5.13
Pathway
rn00220
Arginine biosynthesis
rn00250
Alanine, aspartate and glutamate metabolism
rn01100
Metabolic pathways
Orthology
K01425
glutaminase [EC:
3.5.1.2
]
K01954
carbamoyl-phosphate synthase [EC:
6.3.5.5
]
K01955
carbamoyl-phosphate synthase large subunit [EC:
6.3.5.5
]
K01956
carbamoyl-phosphate synthase small subunit [EC:
6.3.5.5
]
K05597
glutamin-(asparagin-)ase [EC:
3.5.1.38
]
K11540
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:
6.3.5.5
2.1.3.2
3.5.2.3
]
K11541
carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:
6.3.5.5
2.1.3.2
]
K23265
phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:
6.3.5.3
3.5.1.2
]
Other DBs
RHEA:
15892
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