KEGG   REACTION: R00335
Entry
R00335                      Reaction                               
Name
GTP phosphohydrolase
Definition
GTP + H2O <=> GDP + Orthophosphate
Equation
C00044 + C00001 <=> C00035 + C00009
Comment
also hydrolyzing GDP (ec 3.6.1.5, see R00328)
signalling (ec 3.6.5.1)
cell-regulating (ec 3.6.5.2)
mRNA-translation-assisting (ec 3.6.5.3)
protein-synthesis-assisting (ec 3.6.5.4)
vesicle-releasing (ec 3.6.5.5)
microtubule-releasing (ec 3.6.5.6)
Reaction class
RC00002  C00035_C00044
Enzyme
3.6.1.5         3.6.5.1         3.6.5.2         3.6.5.3         
3.6.5.4         3.6.5.5         3.6.5.6
Pathway
rn00230  Purine metabolism
rn01100  Metabolic pathways
rn01232  Nucleotide metabolism
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.5
     R00335  GTP + H2O <=> GDP + Orthophosphate
   3.6.5  Acting on GTP to facilitate cellular and subcellular movement
    3.6.5.1
     R00335  GTP + H2O <=> GDP + Orthophosphate
    3.6.5.2
     R00335  GTP + H2O <=> GDP + Orthophosphate
    3.6.5.3
     R00335  GTP + H2O <=> GDP + Orthophosphate
    3.6.5.4
     R00335  GTP + H2O <=> GDP + Orthophosphate
    3.6.5.5
     R00335  GTP + H2O <=> GDP + Orthophosphate
    3.6.5.6
     R00335  GTP + H2O <=> GDP + Orthophosphate
IUBMB reaction hierarchy [BR:br08202]
 3. Hydrolase reactions
  3.6.1.5
   R02319  Nucleoside triphosphate <=> NDP
    R00335  GTP <=> GDP
Orthology
K01510  apyrase [EC:3.6.1.5]
K14641  apyrase [EC:3.6.1.5]
K14642  golgi apyrase [EC:3.6.1.5]
Other DBs
RHEA: 19672
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