KEGG   REACTION: R00678
Entry
R00678                      Reaction                               
Name
L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
Definition
L-Tryptophan + Oxygen <=> L-Formylkynurenine
Equation
C00078 + C00007 <=> C02700
Reaction class
RC00356  C00078_C02700
Enzyme
1.13.11.11      1.13.11.52
Pathway
rn00380  Tryptophan metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
M00912  NAD biosynthesis, tryptophan => quinolinate => NAD
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.11
     R00678  L-Tryptophan + Oxygen <=> L-Formylkynurenine
    1.13.11.52
     R00678  L-Tryptophan + Oxygen <=> L-Formylkynurenine
Orthology
K00453  tryptophan 2,3-dioxygenase [EC:1.13.11.11]
K00463  indoleamine 2,3-dioxygenase [EC:1.13.11.52]
Other DBs
RHEA: 24539
LinkDB

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