KEGG   REACTION: R00945
Entry
R00945                      Reaction                               

Name
5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
Definition
5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine
Equation
Reaction class
RC00022  C00101_C00143
RC00112  C00037_C00065
Enzyme
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00460  Cyanoamino acid metabolism
rn00630  Glyoxylate and dicarboxylate metabolism
rn00670  One carbon pool by folate
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
Module
M00140  C1-unit interconversion, prokaryotes
M00141  C1-unit interconversion, eukaryotes
M00346  Formaldehyde assimilation, serine pathway
M00532  Photorespiration
Orthology
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Other DBs
RHEA: 15484
LinkDB

KEGG   RCLASS: RC00022
Entry
RC00022                     RClass                                 

Definition
N1b-N1y:*-C1x:C1b+C8y-C1x+C8y
N1x-N1y:*-C1x:C1y+C8y-C1y+C8y
Reactant pair
Related class
Reaction
Enzyme
1.4.1.27        2.1.1.74        2.1.1.148       2.1.2.1         
2.1.2.7         2.1.2.8         2.1.2.10        2.1.2.11        
2.1.5.1
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00670  One carbon pool by folate
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01200  Carbon metabolism
rn01240  Biosynthesis of cofactors
Orthology
K00281  glycine dehydrogenase [EC:1.4.4.2]
K00282  glycine dehydrogenase subunit 1 [EC:1.4.4.2]
K00283  glycine dehydrogenase subunit 2 [EC:1.4.4.2]
K00382  dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
K00605  aminomethyltransferase [EC:2.1.2.10]
K00606  3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
K02437  glycine cleavage system H protein
K03465  thymidylate synthase (FAD) [EC:2.1.1.148]
K19796  dCMP hydroxymethylase [EC:2.1.2.8]
K22578  sesamin methylene transferase [EC:2.1.5.1]

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