REACTION: R01248
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Entry
R01248 Reaction
Name
L-proline:NAD+ 5-oxidoreductase
Definition
L-Proline + NAD+ <=> (S)-1-Pyrroline-5-carboxylate + NADH + H+
Equation
C00148
+
C00003
<=>
C03912
+
C00004
+
C00080
Comment
NADPH (see
R01251
)
Reaction class
RC00001
C00003_C00004
RC00083
C00148_C03912
Enzyme
1.5.1.2
Pathway
rn00330
Arginine and proline metabolism
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01230
Biosynthesis of amino acids
Module
M00972
Proline metabolism
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.2
R01248 L-Proline + NAD+ <=> (S)-1-Pyrroline-5-carboxylate + NADH + H+
BRITE hierarchy
Orthology
K00286
pyrroline-5-carboxylate reductase [EC:
1.5.1.2
]
Other DBs
RHEA:
14108
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