KEGG   REACTION: R01252
Entry
R01252                      Reaction                               
Name
L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating)
Definition
L-Proline + 2-Oxoglutarate + Oxygen <=> Hydroxyproline + Succinate + CO2
Equation
C00148 + C00026 + C00007 <=> C01157 + C00042 + C00011
Reaction class
RC00478  C00148_C01157
Enzyme
1.14.11.2       1.14.11.57
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.2
     R01252  L-Proline + 2-Oxoglutarate + Oxygen <=> Hydroxyproline + Succinate + CO2
    1.14.11.57
     R01252  L-Proline + 2-Oxoglutarate + Oxygen <=> Hydroxyproline + Succinate + CO2
Orthology
K00472  prolyl 4-hydroxylase [EC:1.14.11.2]
Other DBs
RHEA: 51511
LinkDB

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