KEGG   REACTION: R01859
Entry
R01859                      Reaction                               
Name
propanoyl-CoA:carbon-dioxide ligase (ADP-forming)
Definition
ATP + Propanoyl-CoA + HCO3- <=> ADP + Orthophosphate + (S)-Methylmalonyl-CoA
Equation
C00002 + C00100 + C00288 <=> C00008 + C00009 + C00683
Comment
possibly two-step reaction (similar to R00742 or R04385+R04386)
Reaction class
RC00002  C00002_C00008
RC00097  C00100_C00683
RC00609  C00288_C00683
Enzyme
6.4.1.3
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn00630  Glyoxylate and dicarboxylate metabolism
rn00640  Propanoate metabolism
rn00720  Other carbon fixation pathways
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00373  Ethylmalonyl pathway
M00375  Hydroxypropionate-hydroxybutylate cycle
M00376  3-Hydroxypropionate bi-cycle
M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.3
     R01859  ATP + Propanoyl-CoA + HCO3- <=> ADP + Orthophosphate + (S)-Methylmalonyl-CoA
Overall reaction [br08210.html]
 Carbon fixation
  R01859
Orthology
K01964  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K01965  propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
K01966  propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
K11263  acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
K15036  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K15037  biotin carboxyl carrier protein
K15052  propionyl-CoA carboxylase [EC:6.4.1.3 2.1.3.15]
K18472  acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K18603  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K18604  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K18605  biotin carboxyl carrier protein
K19312  acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K22568  acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
K27094  propionyl-CoA/long-chain acyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.3 6.4.1.- 2.1.3.15]
K27095  acyl-CoA carboxylase epsilon subunit
Other DBs
RHEA: 23723
LinkDB

KEGG   RCLASS: RC00097
Entry
RC00097                     RClass                                 
Definition
C1b-C1c:*-C6a:C1a+C5a-C1a+C5a
Reactant pair
C00100_C00683    C00100_C02557    C00109_C06030
Related class
Reaction
R00923 R00930 R00995 R01859 R05373
Enzyme
2.1.3.1         4.1.1.9         4.1.1.112       4.1.1.-         
6.4.1.3
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn00630  Glyoxylate and dicarboxylate metabolism
rn00640  Propanoate metabolism
rn00660  C5-Branched dibasic acid metabolism
rn00720  Other carbon fixation pathways
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Orthology
K01964  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K01965  propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
K01966  propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
K03416  methylmalonyl-CoA carboxyltransferase 5S subunit [EC:2.1.3.1]
K11263  acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
K11264  methylmalonyl-CoA decarboxylase [EC:4.1.1.-]
K15036  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K15037  biotin carboxyl carrier protein
K15052  propionyl-CoA carboxylase [EC:6.4.1.3 2.1.3.15]
K18426  ethylmalonyl-CoA/methylmalonyl-CoA decarboxylase [EC:4.1.1.94 4.1.1.-]
K18472  acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K18603  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K18604  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K18605  biotin carboxyl carrier protein
K19312  acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K22568  acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
K27094  propionyl-CoA/long-chain acyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.3 6.4.1.- 2.1.3.15]
K27095  acyl-CoA carboxylase epsilon subunit

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