KEGG   REACTION: R02477
Entry
R02477                      Reaction                               
Name
androsterone:NADP+ oxidoreductase
Definition
Androsterone + NADP+ <=> 5alpha-Androstane-3,17-dione + NADPH + H+
Equation
C00523 + C00006 <=> C00674 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00144  C00523_C00674
Enzyme
1.1.1.50        1.1.1.209       1.1.1.213       1.1.1.357
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.50
     R02477  Androsterone + NADP+ <=> 5alpha-Androstane-3,17-dione + NADPH + H+
    1.1.1.209
     R02477  Androsterone + NADP+ <=> 5alpha-Androstane-3,17-dione + NADPH + H+
    1.1.1.213
     R02477  Androsterone + NADP+ <=> 5alpha-Androstane-3,17-dione + NADPH + H+
    1.1.1.357
     R02477  Androsterone + NADP+ <=> 5alpha-Androstane-3,17-dione + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.50
   R10423  3alpha-Hydroxysteroid <=> 3-Oxosteroid
    R02477  Androsterone <=> 5alpha-Androstane-3,17-dione
  1.1.1.213
   R10423  3alpha-Hydroxysteroid <=> 3-Oxosteroid
    R02477  Androsterone <=> 5alpha-Androstane-3,17-dione
  1.1.1.357
   R10423  3alpha-Hydroxysteroid <=> 3-Oxosteroid
    R02477  Androsterone <=> 5alpha-Androstane-3,17-dione
Orthology
K00037  3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
K00089  3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
Other DBs
RHEA: 20380
LinkDB

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