KEGG   REACTION: R03176
Entry
R03176                      Reaction                               
Name
3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase
Definition
3beta-Hydroxy-Delta5-steroid + NAD+ <=> 3-Oxo-Delta5-steroid + NADH + H+
Equation
C03836 + C00003 <=> C01034 + C00004 + C00080
Comment
many enzymes also have delta5-delat4-isomerase activity (see ec 5.3.3.1 or R02644) and convert 3beta-hydroxy-delta5-steroid into 3-oxo-delta4-steroid.
general reaction (see R01837, R02216, R02499, R02840, R03327, R04163, R04678, R04849 and R09920)
Reaction class
RC00001  C00003_C00004
RC00144  C01034_C03836
Enzyme
1.1.1.145
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145
     R03176  3beta-Hydroxy-Delta5-steroid + NAD+ <=> 3-Oxo-Delta5-steroid + NADH + H+
Other DBs
RHEA: 24079
LinkDB

KEGG   REACTION: R02644
Entry
R02644                      Reaction                               
Name
3-oxo-delta5-steroid delta5-delat4-isomerase
Definition
3-Oxo-Delta5-steroid <=> 3-Oxo-Delta4-steroid
Equation
C01034 <=> C00619
Comment
many enzymes also have 3-oxidoreductase activity (see ec 1.1.1.145 or R03176) and convert 3beta-hydroxy-delta5-steroid into 3-oxo-delta4-steroid.
general reaction (see R01837, R02216, R02499, R02840, R03327, R04163, R04678, R04849 and R09920)
Reaction class
RC00762  C00619_C01034
Enzyme
5.3.3.1
Brite
Enzymatic reactions [BR:br08201]
 5. Isomerase reactions
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1
     R02644  3-Oxo-Delta5-steroid <=> 3-Oxo-Delta4-steroid
IUBMB reaction hierarchy [BR:br08202]
 5. Isomerase reactions
  5.3.3.1
   R02644  3-Oxo-Delta5-steroid <=> 3-Oxo-Delta4-steroid
Other DBs
RHEA: 14712
LinkDB

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