KEGG   REACTION: R03316
Entry
R03316                      Reaction                               
Definition
3-Carboxy-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + Thiamin diphosphate
Equation
C05381 + C15972 <=> C16254 + C00068
Comment
2-oxoglutarate dehydrogenase complex: oxoglutarate dehydrogenase (see R01700)
TPP-dependent enzymatic reaction (see R00621+R03316)
following after R00621
Reaction class
RC00027  C00068_C05381
RC00627  C15972_C16254
RC02883  C05381_C16254
Enzyme
1.2.4.2
Pathway
rn00020  Citrate cycle (TCA cycle)
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Orthology
K00164  2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
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