KEGG   REACTION: R03630
Entry
R03630                      Reaction                               
Name
phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating)
Definition
Phthalate + Oxygen + NADH + H+ <=> cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+
Equation
C01606 + C00007 + C00004 + C00080 <=> C04783 + C00003
Reaction class
RC00001  C00003_C00004
RC00951  C01606_C04783
Enzyme
1.14.12.7
Pathway
rn00624  Polycyclic aromatic hydrocarbon degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00623  Phthalate degradation, phthalate => protocatechuate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.7
     R03630  Phthalate + Oxygen + NADH + H+ <=> cis-4,5-Dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+
Orthology
K18068  phthalate 4,5-dioxygenase [EC:1.14.12.7]
K18069  phthalate 4,5-dioxygenase reductase component [EC:1.18.1.-]
Other DBs
RHEA: 17492
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