KEGG   REACTION: R03849
Entry
R03849                      Reaction                               
Name
11beta-hydroxyprogesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating)
Definition
11beta-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Corticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Reaction class
RC00157  C02140_C05498
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16
     R03849  11beta-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Corticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.16
   R02130  Steroid <=> 21-Hydroxysteroid
    R03849  11beta-Hydroxyprogesterone <=> Corticosterone
Orthology
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
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