KEGG   REACTION: R04444
Entry
R04444                      Reaction                               
Name
L-1-pyrroline-3-hydroxy-5-carboxylate:NAD+ oxidoreductase
Definition
L-1-Pyrroline-3-hydroxy-5-carboxylate + NAD+ + 2 H2O <=> L-erythro-4-Hydroxyglutamate + NADH + H+
Equation
Comment
possibly two-step reaction (R04443+R05051)
NADPH (see R04445)
Reaction class
RC00001  C00003_C00004
RC00255  C04281_C05947
Enzyme
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Orthology
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Other DBs
RHEA: 31158
LinkDB

KEGG   REACTION: R04445
Entry
R04445                      Reaction                               
Name
L-1-pyrroline-3-hydroxy-5-carboxylate:NADP+ oxidoreductase
Definition
L-1-Pyrroline-3-hydroxy-5-carboxylate + NADP+ + 2 H2O <=> L-erythro-4-Hydroxyglutamate + NADPH + H+
Equation
Comment
possibly two-step reaction
NADH (see R04444)
Reaction class
RC00001  C00005_C00006
RC00255  C04281_C05947
Enzyme
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Orthology
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Other DBs
RHEA: 24946
LinkDB

KEGG   RCLASS: RC00255
Entry
RC00255                     RClass                                 
Definition
C2x-C6a:N2x+*+*-*+O6a+O6a:C1y-C1c
N2x-N1a:C2x-*:C1y-C1c
Reactant pair
Related class
Reaction
Enzyme
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Orthology
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]

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