KEGG   REACTION: R04863
Entry
R04863                      Reaction                               
Name
L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase
Definition
L-2-Aminoadipate adenylate + Holo-Lys2 <=> alpha-Aminoadipoyl-S-acyl enzyme + AMP
Equation
C05560 + C11482 <=> C05535 + C00020
Comment
the second step of three-step reaction (see R03098+R04863+R04390)
for reverse direction, one-step reaction (see R03103)
Reaction class
RC00039  C05535_C11482
RC00070  C00020_C05560
RC02816  C05535_C05560
Enzyme
1.2.1.95
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.95
     R04863  L-2-Aminoadipate adenylate + Holo-Lys2 <=> alpha-Aminoadipoyl-S-acyl enzyme + AMP
Orthology
K00143  L-2-aminoadipate reductase [EC:1.2.1.95]
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