Entry
Symbol
LYS2
Name
L-2-aminoadipate reductase [EC:
1.2.1.95 ]
Pathway
map01110 Biosynthesis of secondary metabolites
Module
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Reaction
R03098 L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase
ATP:L-2-aminoadipate 6-O-adenylyltransferase
R04390 L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase
R04863 L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase
R11679 (S)-2-amino-6-oxohexanoate:NADP+ oxidoreductase (ATP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
K00143 LYS2; L-2-aminoadipate reductase
Enzymes [BR:ko01000 ]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.95 L-2-aminoadipate reductase
K00143 LYS2; L-2-aminoadipate reductase
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Reference
Authors
Ehmann DE, Gehring AM, Walsh CT
Title
Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5.
Journal
Sequence
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