KEGG   REACTION: R06783
Entry
R06783                      Reaction                               
Name
trans-cinnamate,NADH:oxygen oxidoreductase (2,3-hydroxylating)
Definition
trans-Cinnamate + Oxygen + NADH + H+ <=> cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+
Equation
C00423 + C00007 + C00004 + C00080 <=> C12622 + C00003
Comment
HcaA1 HcaA2 HcaC HcaD
Reaction class
RC00001  C00003_C00004
RC00098  C00423_C12622
Enzyme
1.14.12.19
Pathway
rn00360  Phenylalanine metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00545  Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.19
     R06783  trans-Cinnamate + Oxygen + NADH + H+ <=> cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+
Orthology
K00529  3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
K05708  3-phenylpropionate/trans-cinnamate dioxygenase subunit alpha [EC:1.14.12.19]
K05709  3-phenylpropionate/trans-cinnamate dioxygenase subunit beta [EC:1.14.12.19]
K05710  3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin component
Other DBs
RHEA: 25061
LinkDB

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