KEGG   REACTION: R07212
Entry
R07212                      Reaction                               
Name
L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase(3-hydroxylating)
Definition
L-Tyrosine + Tetrahydrobiopterin + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin
Equation
C00082 + C00272 + C00007 <=> C00355 + C15522
Reaction class
RC00046  C00082_C00355
Enzyme
1.14.16.2
Pathway
rn00790  Folate biosynthesis
rn00950  Isoquinoline alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2
     R07212  L-Tyrosine + Tetrahydrobiopterin + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin
Orthology
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Other DBs
RHEA: 18204
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