KEGG   REACTION: R08160
Entry
R08160                      Reaction                               
Name
L-tryptophan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Definition
L-Tryptophan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Indole-3-acetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C00078 + 2 C03024 + 2 C00007 <=> C02937 + 2 C03161 + C00011 + 3 C00001
Comment
three-step reaction (see R09583+R09584+R09585)
Reaction class
RC02295  C00078_C02937
Enzyme
1.14.14.156
Pathway
rn00380  Tryptophan metabolism
rn00966  Glucosinolate biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
Module
M00370  Glucosinolate biosynthesis, tryptophan => glucobrassicin
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.156
     R08160  L-Tryptophan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Indole-3-acetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Orthology
K11812  tryptophan N-monooxygenase [EC:1.14.14.156]
K11813  tryptophan N-monooxygenase [EC:1.14.14.156]
Other DBs
RHEA: 33282
LinkDB

KEGG   REACTION: R08652
Entry
R08652                      Reaction                               
Name
L-phenylalanine,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)
Definition
L-Phenylalanine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (Z)-Phenylacetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C00079 + 2 C00007 + 2 C03024 <=> C16075 + 2 C03161 + C00011 + 3 C00001
Comment
multi-step reaction (see R09579+R09580+R09581+R10041)
Reaction class
RC00001  C00005_C00006
RC02295  C00079_C16075
Enzyme
1.14.14.40
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.40
     R08652  L-Phenylalanine + 2 Oxygen + 2 [Reduced NADPH---hemoprotein reductase] <=> (Z)-Phenylacetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Orthology
K12153  phenylalanine N-monooxygenase [EC:1.14.14.40]
Other DBs
RHEA: 33266
LinkDB

KEGG   REACTION: R08665
Entry
R08665                      Reaction                               
Name
homomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
Homomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 4-Methylthiobutanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C17213 + 2 C03024 + 2 C00007 <=> C17241 + 2 C03161 + C00011 + 3 C00001
Comment
multi-step reaction (similar to R10671, R00730+R04460+R07190)
Reaction class
RC02295  C17213_C17241
Enzyme
1.14.14.42
Pathway
rn00966  Glucosinolate biosynthesis
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.42
     R08665  Homomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 4-Methylthiobutanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.42
   R11646  L-Polyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime
    R08665  Homomethionine <=> 4-Methylthiobutanaldoxime
Orthology
K12154  homomethionine N-monooxygenase [EC:1.14.14.42]
LinkDB

KEGG   REACTION: R08670
Entry
R08670                      Reaction                               
Name
dihomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
Dihomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 5-Methylthiopentanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C17217 + 2 C03024 + 2 C00007 <=> C17245 + 2 C03161 + C00011 + 3 C00001
Comment
multi-step reaction (similar to R10671, R00730+R04460+R07190)
Reaction class
RC02295  C17217_C17245
Enzyme
1.14.14.42
Pathway
rn00966  Glucosinolate biosynthesis
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.42
     R08670  Dihomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 5-Methylthiopentanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.42
   R11646  L-Polyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime
    R08670  Dihomomethionine <=> 5-Methylthiopentanaldoxime
Orthology
K12154  homomethionine N-monooxygenase [EC:1.14.14.42]
Other DBs
RHEA: 32722
LinkDB

KEGG   REACTION: R08672
Entry
R08672                      Reaction                               
Name
trihomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
Trihomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 6-Methylthiohexanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C17221 + 2 C03024 + 2 C00007 <=> C17246 + 2 C03161 + C00011 + 3 C00001
Comment
multi-step reaction (similar to R10671, R00730+R04460+R07190)
Reaction class
RC02295  C17221_C17246
Enzyme
1.14.14.42
Pathway
rn00966  Glucosinolate biosynthesis
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.42
     R08672  Trihomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 6-Methylthiohexanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.42
   R11646  L-Polyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime
    R08672  Trihomomethionine <=> 6-Methylthiohexanaldoxime
Orthology
K12154  homomethionine N-monooxygenase [EC:1.14.14.42]
Other DBs
RHEA: 32726
LinkDB

KEGG   REACTION: R08673
Entry
R08673                      Reaction                               
Name
tetrahomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
Tetrahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 7-Methylthioheptanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C17225 + 2 C03024 + 2 C00007 <=> C17249 + 2 C03161 + C00011 + 3 C00001
Comment
multi-step reaction (similar to R10671, R00730+R04460+R07190)
Reaction class
RC02295  C17225_C17249
Enzyme
1.14.14.42
Pathway
rn00966  Glucosinolate biosynthesis
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.42
     R08673  Tetrahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 7-Methylthioheptanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.42
   R11646  L-Polyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime
    R08673  Tetrahomomethionine <=> 7-Methylthioheptanaldoxime
Orthology
K12154  homomethionine N-monooxygenase [EC:1.14.14.42]
Other DBs
RHEA: 33246
LinkDB

KEGG   REACTION: R08674
Entry
R08674                      Reaction                               
Name
pentahomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
Pentahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 8-Methylthiooctanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C17229 + 2 C03024 + 2 C00007 <=> C17251 + 2 C03161 + C00011 + 3 C00001
Comment
multi-step reaction (similar to R10671, R00730+R04460+R07190)
Reaction class
RC02295  C17229_C17251
Enzyme
1.14.14.42
Pathway
rn00966  Glucosinolate biosynthesis
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.42
     R08674  Pentahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 8-Methylthiooctanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.42
   R11646  L-Polyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime
    R08674  Pentahomomethionine <=> 8-Methylthiooctanaldoxime
Orthology
K12154  homomethionine N-monooxygenase [EC:1.14.14.42]
K12155  homomethionine N-monooxygenase [EC:1.14.14.42]
Other DBs
RHEA: 33294
LinkDB

KEGG   REACTION: R08675
Entry
R08675                      Reaction                               
Name
hexahomomethionine,[NADPH---hemoprotein reductase]:oxygen oxidoreductase
Definition
Hexahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 9-Methylthiononanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C17233 + 2 C03024 + 2 C00007 <=> C17253 + 2 C03161 + C00011 + 3 C00001
Comment
multi-step reaction (similar to R10671, R00730+R04460+R07190)
Reaction class
RC02295  C17233_C17253
Enzyme
1.14.14.42
Pathway
rn00966  Glucosinolate biosynthesis
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.42
     R08675  Hexahomomethionine + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> 9-Methylthiononanaldoxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.42
   R11646  L-Polyhomomethionine <=> omega-(Methylthio)-(E)-alkanal oxime
    R08675  Hexahomomethionine <=> 9-Methylthiononanaldoxime
Orthology
K12154  homomethionine N-monooxygenase [EC:1.14.14.42]
K12155  homomethionine N-monooxygenase [EC:1.14.14.42]
Other DBs
RHEA: 33298
LinkDB

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