KEGG   REACTION: R08160
Entry
R08160                      Reaction                               
Name
L-tryptophan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Definition
L-Tryptophan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Indole-3-acetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Equation
C00078 + 2 C03024 + 2 C00007 <=> C02937 + 2 C03161 + C00011 + 3 C00001
Comment
three-step reaction (see R09583+R09584+R09585)
Reaction class
RC02295  C00078_C02937
Enzyme
1.14.14.156
Pathway
rn00380  Tryptophan metabolism
rn00966  Glucosinolate biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
Module
M00370  Glucosinolate biosynthesis, tryptophan => glucobrassicin
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.156
     R08160  L-Tryptophan + 2 [Reduced NADPH---hemoprotein reductase] + 2 Oxygen <=> Indole-3-acetaldehyde oxime + 2 [Oxidized NADPH---hemoprotein reductase] + CO2 + 3 H2O
Orthology
K11812  tryptophan N-monooxygenase [EC:1.14.14.156]
K11813  tryptophan N-monooxygenase [EC:1.14.14.156]
Other DBs
RHEA: 33282
LinkDB

KEGG   RCLASS: RC02295
Entry
RC02295                     RClass                                 
Definition
C1c-C2b:C6a-*:C1b+N1a-C1b+N2b
N1a-N2b:*-O1b:C1c-C2b
Reactant pair
C00078_C02937    C00079_C16075    C00079_C19714
C00082_C04350    C00123_C17255    C17213_C17241
C17217_C17245    C17221_C17246    C17225_C17249
C17229_C17251    C17233_C17253    C17235_C17236
C21534_C21535
Related class
Reaction
R08160 R08652 R08655 R08664 R08665 R08670 R08672 R08673
R08674 R08675 R09578 R10671 R11646
Enzyme
1.14.13.-       1.14.14.36      1.14.14.40      1.14.14.42      
1.14.14.156
Pathway
rn00380  Tryptophan metabolism
rn00966  Glucosinolate biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM030  Glucosinolate synthesis
Orthology
K11812  tryptophan N-monooxygenase [EC:1.14.14.156]
K11813  tryptophan N-monooxygenase [EC:1.14.14.156]
K12153  phenylalanine N-monooxygenase [EC:1.14.14.40]
K12154  homomethionine N-monooxygenase [EC:1.14.14.42]
K12155  homomethionine N-monooxygenase [EC:1.14.14.42]
K13027  tyrosine N-monooxygenase [EC:1.14.14.36]

DBGET integrated database retrieval system