KEGG   REACTION: R08275
Entry
R08275                      Reaction                               

Definition
Cyclophosphamide + NADPH + H+ + Oxygen <=> 4-Hydroxycyclophosphamide + NADP+ + H2O
Equation
Comment
CYP2B6, CYP2C19, CYP3A4, CYP2C9
Reaction class
RC00001  C00005_C00006
RC02241  C07643_C07888
Enzyme
1.14.14.-
Pathway
rn00982  Drug metabolism - cytochrome P450
Orthology
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17709  cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
K17719  cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
K17721  cytochrome P450 family 2 subfamily C19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.75 1.14.14.-]
LinkDB

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