KEGG   REACTION: R10066
Entry
R10066                      Reaction                               
Name
ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
Definition
ent-Kaurene + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Kaur-16-en-18-oic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Equation
C06090 + 3 C03024 + 3 C00007 <=> C11874 + 3 C03161 + 4 C00001
Comment
three-step reaction (see R06291+R06292+R06293)
Reaction class
RC01952  C06090_C11874
Enzyme
1.14.14.86
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.86
     R10066  ent-Kaurene + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Kaur-16-en-18-oic acid + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Orthology
K04122  ent-kaurene oxidase [EC:1.14.14.86]
K21292  ent-kaurene oxidase [EC:1.14.14.86]
Other DBs
RHEA: 32326
LinkDB

KEGG   REACTION: R06291
Entry
R06291                      Reaction                               
Name
ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
Definition
ent-Kaurene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C06090 + C03024 + C00007 <=> C11872 + C03161 + C00001
Comment
the first step of three-step reaction (see R10066, R06291+R06292+R06293)
Reaction class
RC00257  C06090_C11872
Enzyme
1.14.14.86
Pathway
rn00904  Diterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00927  Gibberellin A12 biosynthesis, GAPP => GA12
M00929  Gibberellin A1 biosynthesis, GGPP => GA1
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.86
     R06291  ent-Kaurene + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-ol + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K04122  ent-kaurene oxidase [EC:1.14.14.86]
K21292  ent-kaurene oxidase [EC:1.14.14.86]
Other DBs
RHEA: 13048
LinkDB

KEGG   REACTION: R06292
Entry
R06292                      Reaction                               
Name
ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
Definition
Kaur-16-en-18-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-al + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C11872 + C03024 + C00007 <=> C11873 + C03161 + 2 C00001
Comment
the second step of three-step reaction (see R10066, R06291+R06292+R06293)
Reaction class
RC00893  C11872_C11873
Enzyme
1.14.14.86
Pathway
rn00904  Diterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00927  Gibberellin A12 biosynthesis, GAPP => GA12
M00929  Gibberellin A1 biosynthesis, GGPP => GA1
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.86
     R06292  Kaur-16-en-18-ol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-al + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Orthology
K04122  ent-kaurene oxidase [EC:1.14.14.86]
K21292  ent-kaurene oxidase [EC:1.14.14.86]
Other DBs
RHEA: 21307
LinkDB

KEGG   REACTION: R06293
Entry
R06293                      Reaction                               
Name
ent-kaur-16-ene,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
Definition
Kaur-16-en-18-al + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-oic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C11873 + C03024 + C00007 <=> C11874 + C03161 + C00001
Comment
the last step of three-step reaction (see R10066, R06291+R06292+R06293)
Reaction class
RC01563  C11873_C11874
Enzyme
1.14.14.86
Pathway
rn00904  Diterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00927  Gibberellin A12 biosynthesis, GAPP => GA12
M00929  Gibberellin A1 biosynthesis, GGPP => GA1
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.86
     R06293  Kaur-16-en-18-al + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Kaur-16-en-18-oic acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K04122  ent-kaurene oxidase [EC:1.14.14.86]
K21292  ent-kaurene oxidase [EC:1.14.14.86]
Other DBs
RHEA: 10931
LinkDB

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