KEGG   REACTION: R10741
Entry
R10741                      Reaction                               
Name
epithienamycin-F,2-oxoglutarate:oxygen oxidoreductase (dehydrating)
Definition
Epithienamycin F + 2-Oxoglutarate + Oxygen <=> Epithienamycin E + Succinate + CO2 + H2O
Equation
C17399 + C00026 + C00007 <=> C11755 + C00042 + C00011 + C00001
Comment
proposed pathway
not yet characterized sufficiently
Reaction class
RC03268  C11755_C17399
Enzyme
1.14.20.-
Pathway
rn00332  Carbapenem biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.20  With 2-oxoglutarate as one donor, and the other dehydrogenated
    1.14.20.-
     R10741  Epithienamycin F + 2-Oxoglutarate + Oxygen <=> Epithienamycin E + Succinate + CO2 + H2O
Orthology
K18565  2-oxoglutarate-dependent dioxygenase [EC:1.14.20.-]
Reference
1  [PMID:24420617]
  Authors
Li R, Lloyd EP, Moshos KA, Townsend CA
  Title
Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009.
  Journal
Chembiochem 15:320-31 (2014)
DOI:10.1002/cbic.201300319
LinkDB

DBGET integrated database retrieval system