KEGG   REACTION: R10794
Entry
R10794                      Reaction                               
Name
monacolin L acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
Definition
Monacolin L acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Monacolin J acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C20853 + C00007 + C03024 <=> C20854 + C03161 + C00001
Reaction class
RC00661  C20853_C20854
Enzyme
1.14.14.125
Pathway
rn00997  Biosynthesis of various other secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00893  Lovastatin biosynthesis, malonyl-CoA => lovastatin acid
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.125
     R10794  Monacolin L acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Monacolin J acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K20980  dihydromonacolin L/monacolin L hydroxylase [EC:1.14.14.124 1.14.14.125]
Other DBs
RHEA: 29602
LinkDB

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