KEGG   REACTION: R11149
Entry
R11149                      Reaction                               
Name
aurachin B:NAD+ 3-oxidoreductase
Definition
Aurachin B + NAD+ + H2O <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+
Equation
C21140 + C00003 + C00001 <=> C21141 + C00004 + C00080
Comment
two-step reaction (see R11148+R11147)
Reaction class
RC00001  C00003_C00004
RC03371  C21140_C21141
Enzyme
1.1.1.394
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00848  Aurachin biosynthesis, anthranilate => aurachin A
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.394
     R11149  Aurachin B + NAD+ + H2O <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+
Orthology
K21271  aurachin B dehydrogenase [EC:1.1.1.394]
LinkDB

KEGG   REACTION: R11147
Entry
R11147                      Reaction                               
Definition
3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+
Equation
C21142 + C00003 <=> C21141 + C00004 + C00080
Comment
first step of two-step reaction (see R11149, R11147+R11148)
Reaction class
RC00001  C00003_C00004
RC03369  C21141_C21142
Enzyme
1.1.1.394
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.394
     R11147  3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD+ <=> 4-Hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH + H+
Other DBs
RHEA: 48731
LinkDB

KEGG   REACTION: R11148
Entry
R11148                      Reaction                               
Definition
Aurachin B + H2O <=> 3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide
Equation
C21140 + C00001 <=> C21142
Comment
spontaneous
second step of two-step reaction (see R11149, R11147+R11148)
Reaction class
RC03370  C21140_C21142
Enzyme
1.1.1.394
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.394
     R11148  Aurachin B + H2O <=> 3,4-Dihydroxy-2-methy-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide
Other DBs
RHEA: 48723 48727
LinkDB

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