KEGG   REACTION: R12546
Entry
R12546                      Reaction                               
Name
thymine,FMNH2:oxygen oxidoreductase (thymine hydroxylating, ring-opening)
Definition
Thymine + Reduced FMN + Oxygen + NADH <=> Methylureidoacrylate + H2O + FMN + NAD+ + H+
Equation
C00178 + C01847 + C00007 + C00004 <=> C20256 + C00001 + C00061 + C00003 + C00080
Comment
three-step reaction (see R12756+R12547+R12539)
Reaction class
RC03558  C00178_C20256
Enzyme
1.14.99.46
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.46
     R12546  Thymine + Reduced FMN + Oxygen + NADH <=> Methylureidoacrylate + H2O + FMN + NAD+ + H+
LinkDB

KEGG   REACTION: R12756
Entry
R12756                      Reaction                               
Definition
Reduced FMN + Oxygen <=> FMN-N5-peroxide
Equation
C01847 + C00007 <=> C22379
Comment
the first step of three-step reaction (see R11164, R12756+R12538+R12539 / R12544, R12756+R12545+R12539 / R12546, R12756+R12547+R12539)
Reaction class
RC03556  C01847_C22379
Enzyme
1.14.14.22      1.14.99.46
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.22
     R12756  Reduced FMN + Oxygen <=> FMN-N5-peroxide
   1.14.99  Miscellaneous
    1.14.99.46
     R12756  Reduced FMN + Oxygen <=> FMN-N5-peroxide
LinkDB

KEGG   REACTION: R12547
Entry
R12547                      Reaction                               
Definition
Thymine + FMN-N5-peroxide <=> Methylureidoacrylate + FMN-N5-oxide
Equation
C00178 + C22379 <=> C20256 + C22238
Comment
the second step of three-step reaction (see R12546, R12756+R12547+R12539)
Reaction class
RC03558  C00178_C20256
Enzyme
1.14.99.46
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.46
     R12547  Thymine + FMN-N5-peroxide <=> Methylureidoacrylate + FMN-N5-oxide
LinkDB

KEGG   REACTION: R12539
Entry
R12539                      Reaction                               
Definition
FMN-N5-oxide + NADH <=> FMN + H2O + NAD+ + H+
Equation
C22238 + C00004 <=> C00061 + C00001 + C00003 + C00080
Comment
spontaneous
the last step of three-step reaction (see R11164, R12756+R12538+R12539 / R12544, R12756+R12545+R12539 / R12546, R12756+R12547+R12539)
Reaction class
RC03554  C00061_C22238
Enzyme
1.14.14.22      1.14.99.46
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.22
     R12539  FMN-N5-oxide + NADH <=> FMN + H2O + NAD+ + H+
   1.14.99  Miscellaneous
    1.14.99.46
     R12539  FMN-N5-oxide + NADH <=> FMN + H2O + NAD+ + H+
LinkDB

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