Acanthamoeba castellanii: ACA1_057010 Help Entry ACA1_057010       CDS       T02667                                  Name (RefSeq) dihydrofolate reductase   KO K13998   dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45] Organism acan  Acanthamoeba castellanii Pathway acan00240   Pyrimidine metabolism acan00670   One carbon pool by folate acan00790   Folate biosynthesis acan01100   Metabolic pathways acan01232   Nucleotide metabolism acan01240   Biosynthesis of cofactors Brite KEGG Orthology (KO) [BR:acan00001]  09100 Metabolism   09104 Nucleotide metabolism    00240 Pyrimidine metabolism     ACA1_057010   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     ACA1_057010    00670 One carbon pool by folate     ACA1_057010 Enzymes [BR:acan01000]  1. Oxidoreductases   1.5  Acting on the CH-NH group of donors    1.5.1  With NAD+ or NADP+ as acceptor     1.5.1.3  dihydrofolate reductase      ACA1_057010  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.45  thymidylate synthase      ACA1_057010 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DHFR_1 Lipase_3 Hydrolase_4 Abhydrolase_1 Abhydrolase_6 Motif Other DBs NCBI-GeneID:  14918545 NCBI-ProteinID:  XP_004339082 UniProt:  L8GV53 LinkDB All DBs Position Unknown AA seq 448 aa AA seqDB search MARTKFSIVVAVATENNAIGVENRLPWHIPKELAAFRTLTRAEGATNAIIMGRRTYELFP NGPLPGRTNIVLSRNPAFEALPGVIVSCDLGSALKKLGVVTEKVFVIGGAQLYREALLHP QCEAIYLTSVSGAPGIEKVDVFFPDIPGDAYKIDVGYAKSGVVHTEVSPITYEYKRYRKA LDEVREARDAIRIASAVDAMYYMISEAYDGVGEMANARASGTGIETLGGLERLANFSLRW DPVGDIVILWRSTSDPTIGFLVFRGMLSAYEWGIDFMYYQVPYEFAVAESGAATPMIHSG FFKAYSSIGASIRRAIVSNGISQLFITGHSLGGALSILAASDLSGLSASGPSAIASAVDV TTFGAPRVGNQAFAAQIHSSRIARILQVRSEDDIVPTTPLSSMVDPARPLGSSLSYEHVG EFVYFRRPQPTIAASHALDNYIGFAMDQ NT seq 1347 nt NT seq  +upstreamnt  +downstreamnt atggcaaggacaaagttcagcatcgtggtggcggtggcgacggagaacaatgcgataggc gttgagaatcggctgccgtggcacatccccaaggagctggcggcgtttcgcacgctgact cgtgctgaaggggccaccaacgcgatcatcatgggccgtcgcacctatgaattgttcccc aacggaccgctgccgggtcgcacgaacatcgtgctctcgaggaaccccgcgtttgaagcg ctgcccggtgtcattgtatcatgtgaccttggatccgcgctcaagaaacttggtgttgtg accgagaaggtttttgtcattggcggtgcccaactctaccgtgaagccctgctacaccca caatgtgaggccatctatctcaccagcgtcagtggcgcccctggcattgagaaggtggat gtgttcttccctgatatacctggagatgcatacaagattgacgtgggctatgccaagagc ggcgtggtacacactgaggtgtctcctatcacctatgagtacaagcgctatcgcaaggcc ttggatgaagtgagggaggcgcgggatgccatccgcattgcatcggccgtggatgccatg tactatatgatctccgaggcttatgatggcgtgggagaaatggccaatgcacgcgcatct ggcactgggattgagacactgggaggcttggagaggttggccaatttttcgctgcgttgg gatcctgtcggcgacatcgtgatcctctggcgatcgaccagcgatcccacgatcggattc ctcgtgtttcgtggcatgttgagcgcctacgagtggggaatagactttatgtactatcag gtcccctacgagtttgccgtcgcagaatccggggcggcgactccgatgatccactctgga ttcttcaaggcctactcgagcatcggcgcctccatccggcgggccatcgtttccaacggc atatcacaactcttcatcaccggacacagtctcggtggtgcgttgtcgatcctggccgca tcggatctcagtgggctctcggcatcgggtccttcggcgatcgccagcgccgtcgacgtg accacctttggtgcaccccgcgtcggcaaccaagcgttcgcggcgcaaatccactcctcg cggatcgccaggatccttcaggtgagatccgaagacgacatcgtgccgacgacgccgctg tcatccatggtcgatcccgcgcgcccgctcggatcgagcctgtcgtacgagcacgtcggt gaattcgtgtactttcgccgaccgcaacccaccatcgcggcatcacacgcactcgacaac tacatcggttttgccatggatcaataa

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