Acanthamoeba castellanii: ACA1_199730 Help Entry ACA1_199730       CDS       T02667                                  Name (RefSeq) dihydrofolate reductase   KO K13998   dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45] Organism acan  Acanthamoeba castellanii Pathway acan00240   Pyrimidine metabolism acan00670   One carbon pool by folate acan00790   Folate biosynthesis acan01100   Metabolic pathways acan01232   Nucleotide metabolism acan01240   Biosynthesis of cofactors Brite KEGG Orthology (KO) [BR:acan00001]  09100 Metabolism   09104 Nucleotide metabolism    00240 Pyrimidine metabolism     ACA1_199730   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     ACA1_199730    00670 One carbon pool by folate     ACA1_199730 Enzymes [BR:acan01000]  1. Oxidoreductases   1.5  Acting on the CH-NH group of donors    1.5.1  With NAD+ or NADP+ as acceptor     1.5.1.3  dihydrofolate reductase      ACA1_199730  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.45  thymidylate synthase      ACA1_199730 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Thymidylat_synt DHFR_1 Motif Other DBs NCBI-GeneID:  14920516 NCBI-ProteinID:  XP_004341781 UniProt:  L8H2H2 LinkDB All DBs Position Unknown AA seq 291 aa AA seqDB search MDTQTPVHPPRPFEIVVAASVNGGIGLAGQLPWQLPQEMARFKALTLKTANDDHSNAVIM GRRTYESIPAKFRPLKGRVNIVLSRDQHRNCVSLPDSVVVASSFDEALLAIQSMEKVQTW PPGSAKITSPEFEVDTFFPQIDPHSFKLDASYPEQGKAHEEKGVTYEMRFSLRDGTFPLL TTKRVWWKGVAEELLWFVSGCTNANTLATKKVNIWKENGSKDFLAKCGLGHREEGDLGPV YGFQWRHWGAKYVDMHTDYSPGIRQTSRKWCCLRATCFASSTLPTASSLVR NT seq 876 nt NT seq  +upstreamnt  +downstreamnt atggatacgcaaactcccgtacatccccctcggccgttcgaaatcgtggtggctgcgtct gtcaatggcggaatcgggctggcaggacagttgccctggcaattgcctcaggagatggcc aggttcaaggccttgactctcaaaacagcaaacgatgaccactcgaacgcggtcattatg ggccggcggacctacgagtcgatccccgcgaaattcagacctctcaagggcagggtcaac atcgtactctcgcgcgaccagcatcgtaattgtgtcagtttgcccgacagcgtggtggtg gcgagtagttttgacgaagcactcctggccatccagagcatggagaaggtgcaaacttgg ccacccggttccgcaaagatcacgtctcccgagttcgaggtagacaccttctttccgcag attgatccgcactctttcaagctcgacgccagctatcctgagcaagggaaggcgcatgaa gaaaagggcgtcacgtatgagatgcggtttagcttgcgggacggcacctttcctctcctc accactaagcgcgtgtggtggaagggggtggccgaggagctcctgtggttcgtgtcgggc tgcacgaatgccaacactttggcaaccaaaaaggtcaacatctggaaggagaacggatcc aaggacttcctcgccaagtgcggacttggccacagagaagagggagacttaggccccgtt tatggcttccagtggaggcactggggagcaaaatacgtggacatgcataccgactactcg cctggaatccgacagacctcaaggaaatggtgttgcctccgtgccacatgttttgccagt tctacgttgccaacggcgagctctcttgtcaggtaa

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