KEGG   Actinidia eriantha (wild kiwifruit): 130779880
Entry
130779880         CDS       T09464                                 
Name
(RefSeq) bifunctional dihydrofolate reductase-thymidylate synthase-like isoform X1
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
aew  Actinidia eriantha (wild kiwifruit)
Pathway
aew00240  Pyrimidine metabolism
aew00670  One carbon pool by folate
aew00790  Folate biosynthesis
aew01100  Metabolic pathways
aew01232  Nucleotide metabolism
aew01240  Biosynthesis of cofactors
Module
aew_M00126  Tetrahydrofolate biosynthesis, GTP => THF
aew_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:aew00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    130779880
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    130779880
   00670 One carbon pool by folate
    130779880
Enzymes [BR:aew01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     130779880
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     130779880
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-GeneID: 130779880
NCBI-ProteinID: XP_057494727
LinkDB
Position
6:complement(19464080..19472024)
AA seq 561 aa
MSLTQGLLRCHKSWSCNLGRKSSYSRLFRVFKSVMAGDTLVNVSNGNLNTKSDPKRTYQV
VVSATQNMGIGKDGKLPWRLPSDIKFFKDVTLTTLDPAKKNAVIMGRKTWESIPLEYRPL
PGRLNVVLTRSGSFDIATAENVVICGSIASSLELLAASPYCLSIEKVFVIGGGQILREAL
NAPGCDAIHVTEIETSIECDTFIPSIDMSAFLPWYSSFPLVENNIRYAFTTYVRVRDSAV
ESISQTNGLISDNSPDYPNLEVKKFSFMPKMIFEKHEEYLYLRLVQDIISTGTPKDDRTG
TGTHSKFGCQMRFNLRKSFPILTTKKVFWRGVVEELLWFISGSTNAKVLQEKGIHIWDGN
ASRDYLDSIGLVDREEGDLGPVYGFQWRHFGARYTSMHADYTGQGFDQLLDVIDKIKNKP
DDRRIILSAWNPSDLKLMALPPCHMFAQFYVTNRELSCQMYQRSADMGLGVPFNIASYAL
LTCMIAHVCDLVPGDFVHVIGDAHVYVNHIRPLQEQLQKLPKPFPMLKINPRKKDIDSFE
AADFKLIGYDPHQKIEMKMAV
NT seq 1686 nt   +upstreamnt  +downstreamnt
atgtcattaacccagggtctgttgcgctgtcacaaaagttggtcgtgtaatctcggtcgc
aagtcttcatattcacgtttgttccgggtttttaaatccgttatggctggtgacactctt
gtgaatgtttctaatggcaatctcaatacaaagtctgacccaaagagaacttaccaagtt
gttgtgtctgcaacccaaaatatgggaattggtaaggatgggaaattaccttggaggttg
ccttcagacatcaaattttttaaggatgttactttgactacattagatcctgcaaaaaag
aatgcagtcattatgggtagaaaaacctgggaaagtattccactggagtatcgtccgtta
ccgggtcgccttaatgttgttctcactcgttctgggagttttgatattgccactgcagag
aatgttgtgatttgtggaagcatcgcttcttctttggagttattggctgcatctccttat
tgcctttcgattgagaaagtgtttgttattggaggtggccagattttgagggaagccttg
aatgctcctggatgtgatgccatccatgttacggaaattgagaccagcattgaatgtgac
actttcatcccttctattgatatgtctgcatttctgccgtggtattcatcctttccattg
gtggaaaacaacattcgctatgcttttactacttatgttcgtgttagggattctgcagtt
gaatccataagtcagaccaatggtctgatatctgataatagcccggattatcccaatctt
gaggtgaagaaattctctttcatgcctaagatgatttttgagaaacatgaggagtatctg
tatctgagactggttcaagacatcatctctactggcactcctaaagatgacagaacaggg
accggtactcattcaaaatttggttgccagatgcgtttcaatctccggaaatcttttcca
attcttacaactaagaaagtattttggcgaggtgttgttgaggaacttctgtggttcatc
agtggttcaacaaatgctaaggtcctacaggaaaagggcattcatatatgggacggcaat
gcatccagagactaccttgatagtattggtttggtggatagagaagaaggtgacttagga
cccgtttatgggttccagtggagacactttggtgctaggtacacaagcatgcatgctgac
tacacaggccaaggatttgatcagttgttagatgttattgacaagatcaagaataagcca
gatgatcgaaggattattctatcagcttggaacccttctgacctcaagttgatggcactt
cccccttgccacatgtttgcccagttctatgtgaccaacagggagttatcatgtcaaatg
tatcagcgctctgctgacatgggtctaggtgtcccgtttaacattgcttcttatgccctc
ttgacgtgcatgattgctcatgtttgtgatcttgttcctggcgattttgtccatgttatt
ggggatgcacatgtttatgtcaatcatataagaccactccaggagcagcttcagaaactt
cctaaaccttttccaatgttgaagatcaatcctcggaagaaggatatagattcctttgag
gcagctgactttaaactcataggttatgatcctcaccagaaaatagaaatgaaaatggct
gtgtag

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