KEGG   Addendum: AEI98659
Entry
AEI98659          CDS       T10000                                 
Symbol
ctcP
Name
(KEGG) tetracycline 7-halogenase (EC:1.14.19.49)
  KO
K14257  tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-]
Taxonomy
TAX:1894
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Kitasatospora
Organism
Kitasatospora aureofaciens
SSDB
Motif
Pfam: FAD_binding_3 Trp_halogenase DAO Lycopene_cycl NAD_binding_8 Pyr_redox_2 FAD_binding_2 Pyr_redox_3 HI0933_like Thi4 Pyr_redox Chitin_bind_4 HCBP_related GDI
Other DBs
NCBI-ProteinID: AEI98659
GB: HM627755
UniProt: A0A1E7MYN1
Structure
LinkDB
AA seq 555 aa
MTDTTADQTRHGDRPYDVVIIGSGLSGTMLGSILAKHGFRIMLLDGAHHPRFAVGESTIG
QTLVVLRLISDRYGVPEIANLASFQDVLANVSSSHGQKSNFGFMFHRDGEEPDPNETSQF
RIPSIVGNAAHFFRQDTDSYMFHAAVRYGCDARQYYRVENIEFDDGGVTVSGADGSTVRA
RYLVDASGFRSPLARQLGLREEPSRLKHHARSIFTHMVGVDAIDDHVDTPAELRPPVPWN
DGTMHHIFERGWMWIIPFNNHPGATNPLCSVGIQLDERRYPARPDLTPEEEFWSHVDRFP
AVQRQLKGARSVREWVRTDRMQYSSSRTVGERWCLMSHAAGFIDPLFSRGLSNTCEIINA
LSWRLMAALREDDFAVERFAYVEELEQGLLDWNDKLVNNSFISFSHYPLWNSVFRIWASA
SVIGGKRILNALTRTKETGDDSHCQALDDNPYPGLWCPLDFYKEAFDELTELCEAVDAGR
TTAEEAARVLEQRVRESDWMLPALGFNDPDTHHINPTADKMIRIAEWATGHHRPEIRELL
AASAEEVRAAMRVKP
Reference
PMID:23800859
  Authors
Zhu T, Cheng X, Liu Y, Deng Z, You D
  Title
Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens.
  Journal
Metab Eng 19:69-78 (2013)
DOI:10.1016/j.ymben.2013.06.003

KEGG   Addendum: AEI98660
Entry
AEI98660          CDS       T10000                                 
Symbol
ctcQ
Name
(KEGG) flavin reductase (NADH)
  KO
K21297  flavin reductase (NADH) [EC:1.5.1.36]
Taxonomy
TAX:1894
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Kitasatospora
Organism
Kitasatospora aureofaciens
SSDB
Motif
Pfam: Flavin_Reduct
Other DBs
NCBI-ProteinID: AEI98660
GB: HM627755
UniProt: S4S3E3 A0A8H9HEL8
Structure
LinkDB
AA seq 191 aa
MPPEPLSLPLDLAPGLVDGDTFLSIMGALPTGVTVVTTLGPDGEPYGLTCSAACSVSKAP
PLLLVCINRDSRVLKALLERGEFAVNVLRGGGESTSARFAAPVDDRFRDVRWEPGSAGGV
PVMSADVVAHAECRVAAALDAGDHTIVIGAVVAGGPRPEVPSPLMYWRRSYARWPVEEDP
RTAALTLAAEG
Reference
PMID:23800859
  Authors
Zhu T, Cheng X, Liu Y, Deng Z, You D
  Title
Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens.
  Journal
Metab Eng 19:69-78 (2013)
DOI:10.1016/j.ymben.2013.06.003

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